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UnknownHigh accuracy barrier heights, enthalpies, and rate coefficients for chemical reactions.
Not available
S-EPMC9293986 | biostudies-literature
ProteomicsTarget Landscape of Clinical Kinase Inhibitors
Here, we provide a comprehensive overview of the selectivity profiles of 242 kinase inhibitors currently in clinical trials. We screened available inhibitors against human protein kinases by using the Kinobead technology resulting in a drug matrix identifying the druggable kinome and related protein...
ORGANISM(S): Homo sapiens (Human) 
2017-12-01 | PXD005336 | Pride
Target Mass spectrometry Chemical proteomics Kinase inhibitors Clinical kinase inhibitors Selectivity Lc-ms/ms 
TranscriptomicsRIPK3 restricts myeloid leukemogenesis by promoting cell death and differentiation of leukemia initiating cells
Examination of gene expression patterns in lineage negative FLT3-ITD– and pMIG-transduced BM cells via microarray study. We performed a global mRNA profiling analysis of murine Lin– FLT3-ITD+ cells compared to empty-vector controls, purified 48h after transduction. We examined association patter...
ORGANISM(S): Mus musculus 
2016-08-22 | E-GEOD-79040 | biostudies-arrayexpress
UnknownSimple, Economic, and Robust Rail-Based Setup for Super-Resolution Localization Microscopy.
Not available
S-EPMC10226110 | biostudies-literature
TranscriptomicsGene expression profiles of mono- and biallelic CEBPA mutations in cytogenetically normal AML
Purpose: CEBPA mutations are found as either biallelic (biCEBPA) or monoallelic (moCEBPA). We set out to explore whether the kind of CEBPA mutation is of prognostic relevance in cytogenetically normal AML (CN-AML). Patients and Methods: 467 homogeneously treated CN-AML patients were subdivided into ...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-15210 | biostudies-arrayexpress
UnknownSmall molecule inhibitors of mammalian glycosylation.
Not available
S-EPMC9713294 | biostudies-literature
UnknownThe role of therapeutic leukapheresis in hyperleukocytotic AML.
Not available
S-EPMC3986260 | biostudies-literature
UnknownFrequency of hematologic and solid malignancies in the family history of 50 patients with acute myeloid leukemia - a single center analysis.
Not available
S-EPMC6472770 | biostudies-literature
TranscriptomicsExpression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia – unexpected expression pattern of the RHO GTPase activator ARHGAP20
In chronic lymphocytic leukemia (CLL), 13q14 and 11q22-23 deletions are found in 2/3 of the cases. 11q22-23 deletions are associated with poor survival, whereas 13q14 deletions as single abnormality are often found in indolent disease forms. The molecular basis for this difference in prognosis is no...
ORGANISM(S): Homo sapiens 
2011-10-13 | E-GEOD-25571 | biostudies-arrayexpress
UnknownTailored Bisacylphosphane Oxides for Precise Induction of Oxidative Stress-Mediated Cell Death in Biological Systems.
Not available
S-EPMC11744658 | biostudies-literature
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