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Proteomicsspint1 specific knokout in mouse pancreas islet SILAC
SPINT1 is a membrane-anchored serine protease inhibitor that modulates pericellular proteolysis. The pancreas-specific disruption of Spint1 in mice significantly decreased islet size and mass, leading to glucose intolerance, which was causally related to the down-regulation of MafA and insulin. Mech...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-01 | PXD039190 | Pride
Spint1 Silac Islet Mouse 
TranscriptomicsNon-tumor/tumor intestinal tissue of control or intestine-specific HAI-1 deficient Apc(Min/+) mice
To analyse roles of HAI-1/Spint1 in intestinal tumorigenesis, we examined the effect of intestine-specific deletion of Spint1 gene on Apc(Min/+) mice. The loss of Hai-1/Spint1 significantly accelerated tumor formation in ApcMin/+ mice and shortened their survival periods. Mouse small intestine tumor...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-40856 | biostudies-arrayexpress
UnknownSPINT1-AS1 Drives Cervical Cancer Progression via Repressing miR-214 Biogenesis.
Not available
S-EPMC8326843 | biostudies-literature
UnknownSpint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA.
Not available
S-EPMC11615295 | biostudies-literature
UnknownComprehensive Analysis of the Expression and Prognostic Value of SPINT1/2 in Breast Carcinoma.
Not available
S-EPMC8351597 | biostudies-literature
UnknownCirculating SPINT1 Is Reduced in a Preeclamptic Cohort with Co-Existing Fetal Growth Restriction.
Not available
S-EPMC8877863 | biostudies-literature
UnknownCirculating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction.
Not available
S-EPMC7228948 | biostudies-literature
UnknownLncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib.
Not available
S-EPMC6391897 | biostudies-literature
UnknownLncRNA SPINT1-AS1 enhances the Warburg effect and promotes the progression of osteosarcoma via the miR-135b-5p/PGAM1 axis.
Not available
S-EPMC11963676 | biostudies-literature
UnknownIntestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2.
Not available
S-EPMC6081401 | biostudies-literature
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