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TranscriptomicsChanges in transcription patterns in BoMac cells in response to PDD spirochetes
Papillomatous digital dermatitis (PDD) is a polymicrobial infection in soft tissue adjacent to the hoof and is the leading cause of lameness in dairy cattle. Treponema phagedenis-like (TPL) spirochetes are a constant feature of PDD lesions and are localized deep in infected tissue. Host-cell respon...
ORGANISM(S): Bos taurus 
2007-06-22 | E-GEOD-6702 | biostudies-arrayexpress
TranscriptomicsIdentification of the differences between gene expression in normal human dermal fibroblasts (NHDF cell line) infected with Borrelia burgdorferi sensu lato spirochetes
The similarity of Lyme borreliosis to other diseases and the complex pathogenesis cause diagnostic and therapeutic difficulties. Changes at the cellular and molecular level after Borrelia sp. infection remain still poorly understood. Therefore, the present study focused on the gene expression in hum...
ORGANISM(S): Homo sapiens 
2015-05-12 | E-GEOD-68741 | biostudies-arrayexpress
ProteomicsA simple non-invasive method to collect soft tick saliva reveals differences in Ornithodoros moubata saliva composition between ticks infected and uninfected with Borrelia duttonii spirochetes
We developed a new simple method to assess the composition of proteins in the Ornithodoros moubata saliva. To collect naturally expectorated saliva from the ticks, we employed an artificial membrane feeding technique using a simple, chemically defined diet and submitted the collected native saliva s...
ORGANISM(S): Ornithodoros moubata Borrelia 
2023-01-10 | PXD038824 | Pride
Relapsing fever borrelia Artificial membrane feeding Ornithodoros moubata Saliva Infected Tick Lc-ms analysis Borrelia duttonii Spirochetes 
TranscriptomicsStage-Specific Alterations in the Transcriptome of Lyme Disease Spirochetes During Tick Feeding and Following Mammalian Host-Adaptation
To compare the transcriptional profiles of Borrelia burgdorferi (Bb) during acquisition (fed larvae), transmission (fed nymphs) and in a mammalian host-like environment (dialysis membrane chambers [DMC]).RNA was isolated from an infected tick (Ixodus scapularis) samples, DMC and in vitro cultures. A...
ORGANISM(S): Borrelia burgdorferi 
2014-12-22 | E-MTAB-2957 | biostudies-arrayexpress
TranscriptomicsChanges in transcription patterns in BoMac cells in response to PDD spirochetes
Papillomatous digital dermatitis (PDD) is a polymicrobial infection in soft tissue adjacent to the hoof and is the leading cause of lameness in dairy cattle. Treponema phagedenis-like (TPL) spirochetes are a constant feature of PDD lesions and are localized deep in infected tissue. Host-cell respons...
ORGANISM(S): Bos taurus 
2007-06-22 | GSE6702 | GEO
UnknownComplement Evasion by Lyme Disease Spirochetes.
Not available
S-EPMC7572514 | biostudies-literature
UnknownElimination of lyme disease spirochetes from ticks feeding on domestic ruminants.
Not available
S-EPMC2976204 | biostudies-literature
GenomicsEpigenomic landscape of Lyme disease spirochetes reveals novel motifs
Epigenomic landscape of Lyme disease spirochetes reveals novel motifs
PRJNA716641 | ENA
UnknownRelapsing fever-like spirochetes infecting European vector tick of Lyme disease agent.
Not available
S-EPMC3000135 | biostudies-literature
UnknownIdentification of spirochetes associated with contagious ovine digital dermatitis.
Not available
S-EPMC2668357 | biostudies-literature
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