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ProteomicsA pore-forming toxin initiates ABI1 complex switching to promote bacterial cell-to-cell spread
Listeria monocytogenes (Lm), a prototypical intracellular bacterial pathogen, expresses ActA to initiate ARP2/3-mediated actin-based motility in the cytosol of host cells. Motile bacteria generate Lm-containing protrusions at the cell surface, facilitating direct cell-to-cell spread and disseminatio...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD074581 | Pride
Cell-to-cell spread Listeria Infectious diseases Ip-ms 
ProteomicsHIV-1 activates T cell signaling independently of antigen to drive viral spread
HIV-1 spreads between CD4 T cells most efficiently through virus-induced cell-cell contacts. To test whether this process potentiates viral spread by activating signaling pathways we developed an approach to analyze the phosphoproteome in infected and uninfected mixed population T cells using differ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD005658 | Pride
T cell Hiv Phosphorylation Virological synapse 
ModelsSmith&Moore2004 - The SIR model for the spread of HongKong Flu
This is the SIR model for disease spread of the Hong Kong flu in New York City in the late 1960's.
2024-09-02 | BIOMD0000001045 | BioModels
TranscriptomicsInduction of epididymis specific G-protein coupled receptor-64 (GPR64) in Ewing Tumors supports invasiveness and metastatic spread
Metastatic spread in Ewing Tumors (ET) is hematogenous and malignant features have been shown to correlate with hypoxia and angiogenesis. We identified several Ewing tumor specific genes (Staege MS et al. Cancer Res. 2004;64:8213-21). Microarray analysis confirmed an endothelial signature of this tu...
ORGANISM(S): Homo sapiens 
2011-09-29 | E-GEOD-23058 | biostudies-arrayexpress
ModelsBertozzi2020 - SIR model of scenarios of COVID-19 spread in CA and NY
The coronavirus disease 2019 (COVID-19) pandemic has placed epidemic modeling at the forefront of worldwide public policy making. Nonetheless, modeling and forecasting the spread of COVID-19 remains a challenge. Here, we detail three regional scale models for forecasting and assessing the course of ...
2024-09-02 | BIOMD0000000956 | BioModels
COVID-19 
TranscriptomicsTranscription profiling of Vibrio cholerae isolated from patients in stationary phase
All arrays used in Hyperinfectivity study Merrell DS, Butler SM, Qadri F, Dolganov NA, Alam A, Cohen MB, Calderwood SB, Schoolnik GK, Camilli A. Related Articles Host-induced epidemic spread of the cholera bacterium. Nature. 2002 Jun 6;417(6889):642-5. PMID: 12050664 A=patient A, B=patient B, C=...
ORGANISM(S): Vibrio cholerae 
2005-07-21 | E-SMDB-1384 | biostudies-arrayexpress
ModelsGiordano2020 - SIDARTHE model of COVID-19 spread in Italy
In Italy, 128,948 confirmed cases and 15,887 deaths of people who tested positive for SARS-CoV-2 were registered as of 5 April 2020. Ending the global SARS-CoV-2 pandemic requires implementation of multiple population-wide strategies, including social distancing, testing and contact tracing. We prop...
2024-09-02 | BIOMD0000000955 | BioModels
COVID-19 
GenomicsComparing nodal versus bony metastatic spread using tumour phylogenies
The role of lymph node metastases in distant prostate cancer dissemination and lethality is ill defined. Patients with metastases restricted to lymph nodes have a better prognosis than those with distant metastatic spread, suggesting the possibility of distinct aetiologies. To explore this, we trace...
EGAS00001001801 | EGA
GenomicsHGSOC origin and spread
Comparative transcriptome analysis links distinct peritoneal tumor spread types, miliary and non-miliary, with putative origin, tubes and ovaries, in high grade serous ovarian cancer
PRJEB17748 | ENA
GenomicsAllosteric effectors of PRC2 synergise to restrict Polycomb domains spread
Allosteric effectors of PRC2 synergise to restrict Polycomb domains spread
PRJNA1168522 | ENA
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