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ProteomicsDeSUMOylase SENP7 mediated epithelial signaling triggers intestinal inflammation via expansion of Gamma-delta T cell
Inflammatory bowel disease (IBD) is a complex autoimmune disorder and recently shown to be associated with SUMOylation, a post-translational modification mechanism. Here we have identified a link between De-SUMOylases and tissue inflammation in IBD. SENP7, a deSUMOylase was seen to be explicitly upr...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD015994 | Pride
Desumoylases Ptms Sumoylation Inflammation Proteomics 
ProteomicsDeSUMOylase SENP7 mediated epithelial signaling triggers intestinal inflammation via expansion of Gamma-delta T cell
Inflammatory bowel disease (IBD) is a complex autoimmune disorder and recently shown to be associated with SUMOylation, a post-translational modification mechanism. Here we have identified a link between De-SUMOylases and tissue inflammation in IBD. SENP7, a deSUMOylase was seen to be explicitly upr...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-05-06 | PXD016018 | Pride
Desumoylases Ptms Sumoylation Inflammation Proteomics 
ProteomicsProteomic Alterations in Multiple Myeloma: A Comprehensive Study Using Bone Marrow Interstitial Fluid and Serum Samples
Multiple myeloma (MM) is a plasma cell associated cancer and the second most common hematological malignancies. Although researchers have been working on MM, comprehensive quantitative proteomic analysis of Bone Marrow Interstitial Fluid (BMIF) and Blood Serum is not yet reported. Being a proximal b...
ORGANISM(S): Homo sapiens (Human) 
2021-01-26 | PXD008927 | Pride
Multiple myeloma Serum biomarkers Swath-ms Bone marrow interstitial fluid Itraq Multipronged quantitative proteomics 2d-dige 
ProteomicsMultipronged quantitative proteomics reveals serum proteome alterations in breast cancer intrinsic subtypes
Being molecularly heterogeneous, breast cancer tends to be a complicated oncological disease with high incidence rates throughout the world. The primary aim of this study was to identify the set of serum proteins with discriminatory capabilities towards the four major subtypes of breast cancer. We e...
ORGANISM(S): Homo sapiens (Human) 
2017-05-15 | PXD006441 | Pride
Dige Swath Serum biomarkers Proteomics Breast cancer Itraq 
MetabolomicsVolatilomic insight of head and neck cancer via the effects observed on saliva metabolites
Head and neck cancer (HNC) is a heterogeneous malignant disease with distinct global distribution. Metabolic adaptations of HNC are significantly gaining clinical interests nowadays. Here, we investigated effects of HNC on differential expression of volatile metabolites in human saliva. We applied h...
2019-06-03 | MTBLS760 | MetaboLights
UnknownHigh-Precision and High-Flux Separation by Rationally Designing the Nanochannels and Surface Nanostructure of Polyamide Nanofiltration Membranes.
Not available
S-EPMC11935859 | biostudies-literature
UnknownApplication of Strategic Transport Model and Google Maps to Develop Better Clot Retrieval Stroke Service.
Not available
S-EPMC6611389 | biostudies-literature
UnknownHeterogeneous off-target impact of ion-channel deletion on intrinsic properties of hippocampal model neurons that self-regulate calcium.
Not available
S-EPMC10613471 | biostudies-literature
TranscriptomicsRNAi knock down of PLC gamma 2, CaMKII, PKC delta and Pyk2 in mouse B cell line A20 after stimulation by anti-IgG to examine the adaptation response of the BCR-dependent intracellular signaling network
We examined the adaptation response of the BCR-dependent intracellular signaling network, to targeted perturbations induced through siRNA-mediated depletion of select signaling intermediates. The robustness of this network was found to derive from the fact that its constituent nodes displayed graded...
ORGANISM(S): Mus musculus 
2008-02-01 | E-TABM-360 | biostudies-arrayexpress
UnknownCorrect identification of oxidized histidine residues using electron-transfer dissociation.
Not available
S-EPMC2737336 | biostudies-literature
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