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MetabolomicsA Multi-omics Longitudinal Study Reveals Alteration of the Leukocyte Activation Pathway in COVID-19 Patients
Severe coronavirus disease 2019 (COVID-19) infection may lead to lung injury, multi-organ failure, and eventually death. Cytokine storm due to excess cytokine production has been associated with fatality in severe infections. However, the specific molecular signatures associated with the elevated im...
2022-01-18 | MTBLS2469 | MetaboLights
MetabolomicsMetabolome and exposome profiling of the biospecimens from COVID-19 patients in India (Nasopharyngeal swab assay)

INTRODUCTION: COVID-19 has become a global impediment by bringing everything to a halt starting from January 2020. India underwent the lockdown starting from 22nd March 2020 with the sudden spike in the number of COVID-19 patients in major cities and states. This study focus...

2022-01-13 | MTBLS2349 | MetaboLights
MetabolomicsMetabolome and exposome profiling of the biospecimens from COVID-19 patients in India (Blood plasma assay)

INTRODUCTION: COVID-19 has become a global impediment by bringing everything to a halt starting from January 2020. India underwent the lockdown starting from 22nd March 2020 with the sudden spike in the number of COVID-19 patients in major cities and states. This study focus...

2022-01-13 | MTBLS2291 | MetaboLights
ProteomicsValidation of proteins showing significant dysregulation from shotgun proteomics experiments in longitudinal plasma samples of COVID-19 patients
A Label Free Quantification study was done to observe the changes in the plasma proteome of patient samples collected at two different time points of disease severity (T1 and T2). A few of the proteins that were significantly dysregulated between the two time points were taken forward for validation...
ORGANISM(S): Homo Sapiens 
2022-06-27 | PXD026848 | panorama
ProteomicsValidation of detected viral and host peptides from COVID-19 nasopharyngeal swab samples
In the current scenario of COVID-19, an assay that can efficiently and specifically detect infection by SARS-COV2 is required. Nasopharyngeal swabs are non-invasive samples and can be conveniently acquired from the population to be screened. In this work, we have validated a few viral and host pepti...
ORGANISM(S): Homo Sapiens Severe Acute Respiratory Syndrome Coronavirus 2 
2021-04-02 | PXD021845 | panorama
ProteomicsAbsolute abundance of human crystallins in lens
Purpose: Measurement of crystallin abundances in human lens has previous relied on poorly reproducible electrophoretic separations or only semi-quantitative mass spectrometry. Therefore, isotope labeled standards were created for all major human lens crystallins so that their absolute abundances cou...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-10-08 | PXD053890 | panorama
ProteomicsSILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors
Mutations mimicking growth factor-induced proliferation and motility characterize aggressive subtypes of mammary tumors. To unravel novel players, we applied phosphoproteomics on untransformed mammary cells, which were pre-stimulated with the epidermal growth factor (EGF). This analysis identified l...
ORGANISM(S): Homo sapiens (Human) 
2019-11-19 | PXD008100 | Pride
Lad1 egf phosphoproteome 
UnknownUnderstanding the long-term impact of the COVID-19 pandemic on non-muscle-invasive bladder cancer outcomes: 12-Month follow-up data from the international, prospective COVIDSurg Cancer study.
Not available
S-EPMC11557269 | biostudies-literature
UnknownImpact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries.
Not available
S-EPMC10783642 | biostudies-literature
UnknownGenomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis.
Not available
S-EPMC9646734 | biostudies-literature
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