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ProteomicsInteraction of Hsp70 Ssb1 and atypical Hsp70 Ssz1
Our goal was to better understand the interaction between the Hsp70 Ssb1 and the atypical Hsp70 Ssz1, which we had uncovered by in vivo site-specific Bpa crosslinking. Ssz1 having Bpa incorporated was purified and incubated with purified Ssb1 and the J-domain protein Zuo1 during activation of photo ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-08-26 | PXD024065 | Pride
Yeast Ssb1 Mass spectrometry Photo crosslinking Ssz1 
TranscriptomicsOverexpression of Ssz1 S295F and Zuo1 amino acids 365-433 S427G in S. cerevisiae
WT strains were transformed with a control TAP plasmid, plasmid containing the Hsp70 chaperones Ssz1 containing a mutation in S295F, or J-domain containing protein Zuo1 amino acids 365-433 with the S427G mutation. These mutations are known to enhance the induction of the pleiotropic drug resistance ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-29 | E-GEOD-31693 | biostudies-arrayexpress
UnknownRole for the molecular chaperones Zuo1 and Ssz1 in quorum sensing via activation of the transcription factor Pdr1.
Not available
S-EPMC3258599 | biostudies-literature
TranscriptomicsOverexpression of SSZ1 suppresses temperature sensitivity phenotype of yeasts indicating its novel function to maintain cellular robustness
Ssz1p plays multifunctional roles in diverse cellular activities including forming a ribosome-associated complex to assist new protein synthesis and activating pleiotropic drug resistance (PDR) pathway. Here we report a novel function of SSZ1 to maintain cellular robustness when it is overexpressed....
ORGANISM(S): Saccharomyces cerevisiae 
2016-12-01 | GSE75557 | GEO
TranscriptomicsOverexpression of Ssz1 S295F and Zuo1 amino acids 365-433 S427G in S. cerevisiae
WT strains were transformed with a control TAP plasmid, plasmid containing the Hsp70 chaperones Ssz1 containing a mutation in S295F, or J-domain containing protein Zuo1 amino acids 365-433 with the S427G mutation. These mutations are known to enhance the induction of the pleiotropic drug resistance ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-30 | GSE31693 | GEO
GenomicsSaccharomyces cerevisiae
Overexpression of SSZ1 suppresses temperature sensitivity phenotype of yeasts indicating its novel function to maintain cellular robustness
PRJNA304591 | ENA
GenomicsSaccharomyces cerevisiae
Overexpression of Ssz1 S295F and Zuo1 amino acids 365-433 S427G in S. cerevisiae
PRJNA145365 | ENA
OtherA functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae
Proteostasis is a fundamental network of cellular pathways that ensures the optimal concentration and composition of correctly folded proteins within cells in normal and stress conditions. Among key components of this network are the molecular chaperones, which mediate protein folding but also act a...
ORGANISM(S): Saccharomyces cerevisiae 
2020-11-25 | GSE151632 | GEO
TranscriptomicsStudy of ribosome dynamics of rpl3[W255C] and its interactions with ribosome-associated chaperones
Proteostasis is a fundamental network of cellular pathways that ensures the optimal concentration and composition of correctly folded proteins within cells in normal and stress conditions. Among key components of this network are the molecular chaperones, which mediate protein folding but also act a...
ORGANISM(S): Saccharomyces cerevisiae 
2020-11-25 | GSE114899 | GEO
UnknownThe ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Not available
S-EPMC7083937 | biostudies-literature
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