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MetabolomicsGut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice
Meta-analyses suggest that yogurt consumption reduces type 2 diabetes incidence in humans, but the molecular basis of these observations remains unknown. Here we show that dietary yogurt intake preserves whole-body glucose homeostasis and prevents hepatic insulin resistance and liver steatosis in a ...
2022-02-03 | MTBLS442 | MetaboLights
TranscriptomicsGene profiling during symbiosis between the actinorhizal tree Alnus glutinosa and the actinobacteria Frankia alni ACN14
Alnus glutinosa belongs to a family of angiosperms called actinorhizal plants because they can develop nitrogen-fixing nodules in association with the soil bacteria Frankia. The aim of this transcriptomic study was to get a global view of the plant symbiotic genetic program and to identify new key p...
ORGANISM(S): Alnus glutinosa 
2011-04-11 | E-GEOD-24153 | biostudies-arrayexpress
TranscriptomicsGene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing.
Purpose: Calcific aortic valve stenosis (AS) is a fatal disease with currently no medical therapy. Some genes were associated with AS, but the genetic architecture of the disease has yet to be discovered. The objective of this study was to combine genome-wide association studies (GWAS) and gene expr...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-55492 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human nasal NK/T-cell Lymphoma (8 tumor samples, 2 cell lines)
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 8 NKTCL biopsies, 2 NKTCL cell lines. Biopsies and cell lines of NK/T-cell lymphoma, nasal-type (NKTCL) were subject to combine...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-791 | biostudies-arrayexpress
UnknownAutochthonous eukaryotic diversity in hydrothermal sediment and experimental microcolonizers at the Mid-Atlantic Ridge.
Not available
S-EPMC141059 | biostudies-literature
TranscriptomicsTranscription profiling of human invasive and non-invasive non-functioning pituitary adenomas
Context : Non Functioning Pituitary Adenomas (NFPAs), although typically benign, may be locally invasive. Few datas are currently available related to the molecular process of invasion in sporadic pituitary adenomas. Markers of invasiveness, important for helping the clinician in the therapeutic s...
ORGANISM(S): Homo sapiens 
2010-03-18 | E-TABM-899 | biostudies-arrayexpress
TranscriptomicsQuantitative transcriptomic analysis of wild type and metabolic mutants of Clostrdidium acetobutylicum ATCC824 under different physiological conditions
Transcriptomic analysis was applied to acidogenic, solventogenic and alcohologenic steady-state C. acetobutylicum cells for understanding the regulation of the metabolism of this organism. Used microarray is Clostridium acetobutylicum ATCC824 transcriptional 44k v4, correspondance to GPL10908 Phosph...
ORGANISM(S): Clostridium acetobutylicum ATCC 824 
2015-07-01 | E-GEOD-69973 | biostudies-arrayexpress
TranscriptomicsPrognostic significance of copy-number alterations in multiple myeloma
Purpose Chromosomal aberrations are a hallmark of multiple myeloma but their global prognostic impact is largely unknown. Methods We performed a genome-wide analysis of malignant plasma cells from 192 newly myeloma patients using high-density, single-nucleotide polymorphism (SNP) arrays to identify...
ORGANISM(S): Homo sapiens 
2009-08-19 | E-GEOD-12896 | biostudies-arrayexpress
TranscriptomicsGene expression profile alone is inadequate in predicting complete response in multiple myeloma
We have analyzed gene expression microarray datasets from four different clinical trials to assess accuracy of gene expression based signature in predicting treatment complete response in patients with multiple myeloma. Two of four datasets were made available via The Intergroupe Francophone du Myél...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-55145 | biostudies-arrayexpress
TranscriptomicsIGR_JUNCONCO_STUDY_LM
Antineoplastic effects of siRNA against TMPRSS2-ERG junction oncogene in prostate cancer: from molecular and cellular studies to preclinical investigations. Background of the study.:TMPRSS2-ERG junction oncogene is present in more than 50% of patients with prostate cancer, and its expression is freq...
ORGANISM(S): Homo sapiens 
2015-01-09 | E-MTAB-2838 | biostudies-arrayexpress
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