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MetabolomicsMetabolomic determinants of carotid atherosclerosis plaque stability
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
2025-06-06 | MTBLS12303 | MetaboLights
MetabolomicsDoes Storage Post Sampling Influence the Stability of Sebum when used for Mass Spectrometry Metabolomics Analysis?

Sebum is a biofluid excreted by sebaceous glands in the skin. In recent years sebum has been shown to contain endogenous metabolites diagnostic of disease, with remarkable results for Parkinson’s Disease. Given that sebum sampling is facile and non-invasive, its potential for use in clinical bioc...

2025-07-15 | MTBLS7946 | MetaboLights
MetabolomicsCore microbes are ecological generalists supporting the host and ecosystem functionality and stability
Core gut microbes persist across diverse gut ecosystems, raising the central question in microbiome research of what defines core microbes and the factors driving their persistence across hosts? Using the rumen microbiome as a model system, our study reveals that core microbes exhibit distinct attri...
2025-05-23 | MTBLS11446 | MetaboLights
MetabolomicsNarrow-spectrum resource-utilizing bacteria drive the stability of synthetic communities through enhancing metabolic interactions
The importance of synthetic microbial communities in agriculture is increasingly being recognized, but methods for constructing targeted synthetic communities using existing microbial resources remain limited. In this study, six plant beneficial bacterial strains with distinct capacities for utilizi...
2025-07-11 | MTBLS12572 | MetaboLights
MetabolomicsHigh-throughput carotenoid profiling using multivariate curve resolution (Stability of isoprenoids in grape extract)
We present automated data analysis of high throughput high-performance liquid chromatography with diode array detection (HPLC-DAD) data using multivariate curve resolution. This technique provides spectra and elution profiles of all UV-Vis active compounds present in the mixture. The specifics of us...
2014-07-01 | MTBLS85 | MetaboLights
MetabolomicsThe stability and functional redundancy of a microbial cheese ecosystem subjected to a biotic perturbation
The cheese microbial community is dense with relatively low complexity and composed of cultivable prokaryotic and eukaryotic microorganisms. The ripening process can thus be reproduced under controlled conditions. A reduced microbial community composed of yeasts and bacteria was assembled to mimic t...
2024-04-29 | MTBLS6968 | MetaboLights
MetabolomicsTime-dependent stability of plasma and liver interstitial fluid metabolites during sample handling in mice

This study assesses the stability of metabolite levels in plasma and liver interstitial fluid (IF) from mice subjected to different handling times prior to extraction. Blood and tissues from female C57BL/6J mice were collected and either processed immediately or held on ice for 5, 10, or 30 minut...

2025-12-30 | MTBLS13164 | MetaboLights
MetabolomicsStability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation
Inflammatory bowel disease (IBD) is associated with altered microbiota composition and metabolism, but it is unclear whether these changes precede inflammation or are the result of it since current studies have mainly focused on changes after the onset of disease. We previously showed differences in...
2017-07-14 | MTBLS432 | MetaboLights
TranscriptomicsRole of mRNA stability during bacterial adaptation
Bacterial adaptation involves extensive cellular reorganization. In particular, growth rate adjustments are associated with substantial modifications of gene expression and mRNA abundance. In this work we aimed to assess the role of mRNA degradation during such variations. A genome-wide transcript...
ORGANISM(S): Lactococcus lactis 
2014-06-16 | E-GEOD-43875 | biostudies-arrayexpress
MetabolomicsMetabolomic and Metataxonomic Fingerprinting of Human Milk Suggests Compositional Stability over a Natural Term of Breastfeeding to 24 Months
Sparse data exist regarding the normal range of composition of maternal milk beyond the first postnatal weeks. This single timepoint, observational study in collaboration with the 'Parenting Science Gang' citizen science group evaluated the metabolite and bacterial composition of human milk from 62 ...
2022-02-11 | MTBLS1370 | MetaboLights
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