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To better understand how mechanical signals influence liver cancer cell behavior, we employed transcriptomic analysis using bulk RNA sequencing. Alexander, HepG2, and Huh7 cells were cultured for 48 hours on ESS dishes with varying stiffness to assess their global transcriptional responses to differ...
ORGANISM(S): Homo sapiens 

Bulk high-resolution mass spectrometry can provide sensitive and global snapshots of metabolites involved in cancer metabolism. However, intra-tumor heterogeneity (IntraTH) convolutes the cellular origins and tumor pathologies associated with the detected metabolites, thus making the elucidation ...

2026-04-15 | MTBLS13432 | MetaboLights
Cellular mechanisms that contribute to low estradiol concentrations produced by the preovulatory ovarian follicle in cattle with a compromised metabolic status (such as lactatino) are largely unknown. To gain insight into the main metabolic mechanisms affecting preovulatory follicle function RNAseq ...
ORGANISM(S): Bos taurus 
In natural environments, plants have to deal with a wide range of different herbivores whose communities vary in time and space. It is believed that the chemical diversity within plant species has mainly arisen from selection pressures exerted by herbivores. So far, the effects of chemical diversity...
2019-06-17 | MTBLS738 | MetaboLights
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