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TranscriptomicsMouse MOV10L1 associates with Piwi proteins and is an essential component of the piRNA pathway
Piwi-interacting RNAs (piRNAs) are essential for silencing of transposable elements in the germline but their biogenesis is poorly understood. Here we demonstrate that MOV10L1, a germ cell-specific putative RNA helicase, is associated with Piwi proteins. Genetic disruption of the MOV10L1 RNA helicas...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-21763 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of gene expression following irradiation to identify P53 activity
The purpose of the experiment was to generate a time course of gene expression following irradiation. The goal was then to model this data to extract hidden variables - chiefly, the activity profiles of the p53 transcription factor. Using this information the aim was to predict which transcripts cha...
ORGANISM(S): Homo sapiens 
2006-03-01 | E-MEXP-549 | biostudies-arrayexpress
TranscriptomicsThe TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline
We identify small RNA partners of Mili from 14 dpp testes of Tdrd9-/- and Tdrd9+/- mice. Two technical replicates of the same library are indicated as replicate 1 and 2. Examination of differences in Mili-associated RNAs in 14 dpp testes of Tdrd9-/- and Tdrd9+/- mice
ORGANISM(S): Mus musculus 
2010-01-06 | E-GEOD-18825 | biostudies-arrayexpress
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
TranscriptomicsLoss of the Mili-interacting Tdrd1 activates transposons and alters Mili-associated small RNA profile
Piwi proteins and their associated Piwi-interacting RNAs (piRNAs) are implicated in transposon silencing in the murine germline. There is currently little information on additional proteins in the murine Piwi complex and how they might regulate the entry of transcripts that accumulate as piRNAs in t...
ORGANISM(S): Mus musculus 
2009-05-24 | E-GEOD-16023 | biostudies-arrayexpress
UnknownAntibacterial Activity of Small Molecules Which Eradicate Methicillin-Resistant Staphylococcus aureus Persisters.
Not available
S-EPMC8846302 | biostudies-literature
UnknownPropagation of Photoinduced Electric Field Changes Through Phytochrome and their Impact on Conformational Transitions.
Not available
S-EPMC12640670 | biostudies-literature
UnknownHydrogen Bonding and Noncovalent Electric Field Effects in the Photoconversion of a Phytochrome.
Not available
S-EPMC11613453 | biostudies-literature
UnknownA new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson's disease.
Not available
S-EPMC8607441 | biostudies-literature
UnknownCharacterizing molecular and synaptic signatures in mouse models of late-onset Alzheimer's disease independent of amyloid and tau pathology.
Not available
S-EPMC11180851 | biostudies-literature
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