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TranscriptomicsPancreatic islet expression profiling in diabetes prone C57BLKS/J mice vs C57BL6/J mice.
C57BLKS/J mice are susceptible to diabetes, because of islet dysfunction, whereas C57BL6/J mice are not. Differences in gene expression between the two strains may account for this sensitivity. Furthermore these differences may only be evident in the hyperstimulated (diabetic or hyperglycemic) state...
ORGANISM(S): Mus musculus 
2008-12-30 | E-GEOD-11257 | biostudies-arrayexpress
ProteomicsPptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-29 | PXD012743 | Pride
Mitochondia Pptc7 Phosphoproteome 
UnknownUnderstanding Provider Treatment Approaches for the Provision of Gender-Affirming Hormones in the Current US Political Climate.
Not available
S-EPMC12424504 | biostudies-literature
MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
UnknownSynaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression.
Not available
S-EPMC11833719 | biostudies-literature
UnknownBuprenorphine reverses neurocognitive impairment in EcoHIV infected mice: A potential therapy for HIV-NCI.
Not available
S-EPMC9585248 | biostudies-literature
UnknownNarrow Dialysis Networks In Medicare Advantage: Exposure By Race, Ethnicity, And Dual Eligibility.
Not available
S-EPMC10837791 | biostudies-literature
UnknownEffect of aging on stem cells.
Not available
S-EPMC5316899 | biostudies-literature
UnknownLimited Medigap Consumer Protections Are Associated With Higher Reenrollment In Medicare Advantage Plans.
Not available
S-EPMC6541000 | biostudies-literature
ProteomicsWnt signaling inhibits Casein kinase 1a activity by modulating its interaction with Protein phosphatase 2A
The mechanism by which Wnt signaling, an essential pathway controlling development and disease, stabilizes beta-Catenin has been a subject of debate over the last three decades. Casein kinase 1alpha (CK1a) functions as a pivotal negative regulator of this signaling pathway, initiating the events tha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000095904 | MassIVE
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