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ProteomicsComplexome Profiling of the mitochondrial proteome from Viscum album
Recent genomic studies revealed that mitochondria from mistletoe species appear to lack a major amount of genes, indicating a possible loss of the NADH ubiquinone oxidoreductase (complex I) which forms an essential part of the mitochondrial Oxidative Phosphorylation System (OXPHOS). This dataset is ...
ORGANISM(S): Viscum album 
2018-04-23 | PXD008974 | Pride
Mitochondria Mistletoe Proteome Lc-msms Blue native Viscum album 
TranscriptomicsExpression data for Mobilized Peripheral Blood CD34+ cells with Wnt or BMP stimulation
Analysis of mobilized peripheral blood CD34+ cells from a healthy volunteer under erythroid differentiation conditions with and without stimulation to the BMP or Wnt signaling pathways. For erythroid differentiation, expanded CD34+ cells were placed in Stemspan SFEM medium supplemented with 2% pen/s...
ORGANISM(S): Homo sapiens 
2011-10-06 | E-GEOD-26351 | biostudies-arrayexpress
TranscriptomicsintDCs versus LCs
miRNA profiling of CD34+ derived, in vitro-generated Langerhans cells (LCs) and interstitial-type dendritic cells (intDCs). Epidermal Langerhans cells (LCs) form a network of dendritic cells (DCs) in basal/suprabasal layers of the skin and are characterized by a unique phenotype (CD207+ CD1abright C...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-20215 | biostudies-arrayexpress
ProteomicsFunctional Assessment of US SARS-CoV-2 L452R Epsilon Variant
The multiple mutations comprising the epsilon variant demonstrates the independent convergent evolution of SARS-CoV-2 with its spike protein mutation L452R also present in the delta variant. Cells infected with live viral samples of the epsilon viral variant compared to non-epsilon variant displa...
ORGANISM(S): Chlorocebus sabaeus 
2022-05-06 | PXD027995 | Pride
Faims Covid19 Vero 
TranscriptomicsProtective Role of IL-10 in Ozone-induced Pulmonary Inflammation
Background: The mechanisms underlying ozone (O3)-induced pulmonary inflammation remain unclear. Interleukin (IL)-10 is an anti-inflammatory cytokine that is known to inhibit inflammatory mediators. Objectives: The current study investigated the molecular mechanisms underlying IL-10-mediated attenua...
ORGANISM(S): Mus musculus 
2011-10-18 | E-GEOD-25095 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression in lineage specific hematopoiesis
MicroRNA plays a critical role in a wide variety of biological processes and regulate genes associated with different biological processes such as development, proliferation, apoptosis, stress response, and tumourigenesis. Profiling miRNA expression during differentiation of embryonic stem cells wil...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-35532 | biostudies-arrayexpress
TranscriptomicsTranscriptome Profiling and Sequencing of differentiated Human Hematopoietic Stem cells Reveal Lineage Specific Expression and Alternative Splicing of Genes
Hematopoietic differentiation is strictly regulated by complex network of transcription factors that are controlled by ligands binding to cell surface receptors. Disruptions of the intricate sequences of transcriptional activation and suppression of multiple genes cause hematological diseases, such...
ORGANISM(S): Homo sapiens 
2011-11-22 | E-GEOD-29989 | biostudies-arrayexpress
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