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UnknownSimultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.
Not available
S-EPMC4889708 | biostudies-literature
UnknownDifferential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages.
Not available
S-EPMC554806 | biostudies-literature
TranscriptomicsTranscription profiling of wheat GF-transgenic-B102,1-1 vs control-L88-31 lines endosperm tissue (14 and 28 days post anthesis-dpa) and in leaf tissue (8 days post germination ?dpg)
The high molecular weight (HMW) subunits of wheat glutenin are synthesised only in the starchy endosperm tissue of the developing wheat grain. We studied the effect of introducing transgenes on the global gene expression profiles of selected transgenic wheat lines, particularly during wheat seed dev...
ORGANISM(S): Triticum aestivum 
2005-10-05 | E-MEXP-306 | biostudies-arrayexpress
UnknownChromosome 10q26-driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium.
Not available
S-EPMC8325339 | biostudies-literature
ProteomicsKinase Selectivity Profiling of anti-MRSA Diarylimidazoles in HEK293 Cells
Antimicrobial resistance (AMR) is widely acknowledged as one of the most serious public health threats facing the world, yet the private sector finds it challenging to generate much-needed medicines. As an alternative discovery approach, a small array of diarylimidazoles was screened against the ESK...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD040208 | Pride
Diarylimidazole Mib-ms Kinases Hek293 Antimicrobials 
ProteomicsA novel method for creating a synthetic L-DOPA proteome and in vitro evidence of incorporation.
Proteinopathies are protein misfolding diseases that have an underlying factor that effect the conformation of proteoforms. A factor hypothesised to play a role in these diseases is the incorporation of non-protein amino acids into proteins, with a key example being the therapeutic drug levodopa. Th...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025759 | Pride
Misincorporation  post translational modifications  ptm  levodopa  l-dopa 
UnknownLevels of complement factor H-related 4 protein do not influence susceptibility to age-related macular degeneration or its course of progression.
Not available
S-EPMC10781981 | biostudies-literature
ProteomicsHypoxic injury triggers maladaptive repair in human kidney organoids
Reduction in blood supply to the kidneys occurs to certain extent during kidney injury (AKI). Individuals who suffered AKI are at risk of developing chronic kidney disease (CKD) through a maladaptive repair process. At present, no therapies exist to prevent the AKI to CKD transition. Here, we presen...
ORGANISM(S): Homo sapiens (Human) 
2026-06-26 | PXD042882 | Pride
Acute kidney injury Metabolomics Organoids Chronic kidney disease Transcriptomics Maladaptive regeneration Proteomics Hypoxia 
UnknownASSESSING THE POTENTIAL EFFECTS OF FUNGICIDES ON NONTARGET GUT FUNGI (TRICHOMYCETES) AND THEIR ASSOCIATED LARVAL BLACK FLY HOSTS.
Not available
S-EPMC4570023 | biostudies-literature
TranscriptomicsEffect of Dietary Grain on Rumen Papillae Gene Expression in Holstein Dairy Cows
Four mature, non-lactating dairy cattle were transitioned from a high forage diet (HF; 0% grain) to a high grain diet (HG; 65% grain) that was fed for three weeks. Rumen papillae biopsies were performed during the HF baseline (week 0) and after the first (week 1) and third week (week 3) of the grai...
ORGANISM(S): Bos taurus 
2009-08-28 | E-GEOD-17849 | biostudies-arrayexpress
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