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UnknownFirst implication of STRA6 mutations in isolated anophthalmia, microphthalmia, and coloboma: a new dimension to the STRA6 phenotype.
Not available
S-EPMC3918001 | biostudies-literature
ProteomicsMolecular basis of mitogen-activated protein kinase ERK2 activation by its upstream kinase MEK1
The RAS-RAF-MEK-ERK mitogen-activated protein kinase (MAPK) pathway relays extracellular signals into a cellular response and its dysregulation leads to many pathologies, particularly cancer. Here, we determined cryo-EM structures of the MAP2K MEK1 activating its substrate MAPK ERK2, the final event...
ORGANISM(S): Homo sapiens (Human) 
2026-10-20 | PXD073457 | Pride
Cellular signalling Protein kinases Phosphorylation 
ProteomicsCaulobacter crescentus GsrN overexpression proteome during hyperosmotic stress
In order to better define the global regulatory effects of the sRNA, GsrN, in Caulobacter crescentus during hyperosmotic stress, we submitted soluble lysates from a gsrN over-expression stain , as well as, a wild-type sample for LC-MS/MS analysis.
ORGANISM(S): Caulobacter crescentus CB15 
2019-11-12 | PXD010072 | Pride
Caulobacter crescentus Sucrose Srna overexpression Hyperosmotic stress 
UnknownTrial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.
Not available
S-EPMC4872347 | biostudies-literature
ProteomicsMAP2Ks can activate MAP kinases using ADP in vitro
Kinases are a diverse group of enzymes that use ATP to phosphorylate a variety of substrates. Protein kinases evolved in eukaryotes as important mediators of cell signalling that target specific amino acid side chains to modulate downstream protein function. Among them, the MAPKs (mitogen-activated ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2025-09-29 | PXD065314 | Pride
Kinase Adp Phosphorylation Mapk 
UnknownImpact of centre volume, surgeon volume, surgeon experience and geographic location on reoperation after intramedullary nailing of tibial shaft fractures
Not available
S-EPMC8410470 | biostudies-literature
TranscriptomicsOutcomes of Allogeneic Hematopoietic Cell Transplantation in Adults with fusions associated with Ph-like ALL
Allogenic hematopoietic cell transplantation (alloHCT) is a well-established curative modality for adults with high-risk ALL; yet large data describing alloHCT outcomes in Philadelphia (Ph)-like ALL is lacking. We retrospectively analyzed archived DNA samples from consecutive adults with B-cell Ph-n...
ORGANISM(S): Homo sapiens 
2022-08-01 | E-MTAB-11954 | biostudies-arrayexpress
UnknownMethotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
Not available
S-EPMC4486345 | biostudies-literature
GenomicsEGAS00001000775-sc-20180926 - samples
DDD DATAFREEZE 2017-12-15: 13,462 trios and probands only - exome sequence VCF files
EGAD00001004389 | EGA
GenomicsEGAS00001000775-sc-20181010 - samples
DDD DATAFREEZE 2017-12-15: 13,462 trios and probands only - phenotypic and family descriptions
EGAD00001004388 | EGA
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