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MetabolomicsSingle-cell and bulk level metabolomic study of the glycolysis inhibition by 2-deoxy-D-glucose in Saccharomyces cerevisiae
Single-cell level measurements are necessary to characterize the intrinsic biological variability in a population of cells. In a study of the metabolic response of a clonal Saccharomyces cerevisiae population challenged by the glycolytic inhibitor 2-deoxy-D-glucose (2-DG), this variability is shown ...
2013-05-22 | MTBLS29 | MetaboLights
TranscriptomicsTranscription profiling of human TLR2/1 stimulated human monocytes with the Mycobacterium tuberculosis derived 19kDa lipopeptide reveals Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular bacteria, which in murine, but not human, monocytes and macrophages is mediated principally by nitric oxide. We report here that TLR activation of human macrophages up-re...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-8921 | biostudies-arrayexpress
ProteomicsComprehensive analysis of C. glutamicum anaplerotic deletion mutants under defined D-glucose conditions
Wild-type C. glutamicum ATCC 13032 is known to possess two enzymes with anaplerotic (C4-directed) carboxylation activity, namely phosphoenolpyruvate carboxylase (PEPCx) and pyruvate carboxylase (PCx). On the other hand, C3-directed decarboxylation can be catalyzed by the three enzymes phosphoenolpyr...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2021-09-09 | PXD022622 | Pride
Methylcitrate cycle Phosphoenolpyruvate carboxykinase Corynebacterium glutamicum Oxaloacetate decarboxylase Pyruvate carboxylase Anaplerosis Malic enzyme Phosphoenolpyruvate carboxylase 
TranscriptomicsGene expression variation in African and European populations of Drosophila melanogaster
Background: Differences in levels of gene expression among individuals are an important source of phenotypic variation within populations. Recent microarray studies have revealed that expression variation is abundant in many species, including Drosophila melanogaster. However, previous expression su...
ORGANISM(S): Drosophila melanogaster 
2008-01-20 | E-GEOD-8843 | biostudies-arrayexpress
GenomicsGenome-wide analysis of hepatic cells upon infection with Hepatitis B virus (HBV) or Hepatitis D virus (HDV)
Genome-wide analysis of hepatic cells upon infection with Hepatitis B virus (HBV) or Hepatitis D virus (HDV)
PRJNA432087 | ENA
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
UnknownEvidence for a selective sweep in the wapl region of Drosophila melanogaster.
Not available
S-EPMC1456153 | biostudies-literature
UnknownCyclophilin D plays a critical role in the survival of senescent cells.
Not available
S-EPMC11612481 | biostudies-literature
UnknownCancer burden and risk factors among women with HIV: a multi-regional study from the D:A:D and RESPOND cohort collaborations.
Not available
S-EPMC12818069 | biostudies-literature
UnknownSimple Purification of Nicotiana benthamiana-Produced Recombinant Colicins: High-Yield Recovery of Purified Proteins with Minimum Alkaloid Content Supports the Suitability of the Host for Manufacturing Food Additives.
Not available
S-EPMC5796045 | biostudies-literature
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