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UnknownThe frequency of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC): routine screening data for central Europe from a cohort study.
Not available
S-EPMC3641502 | biostudies-literature
ProteomicsChemical proteomics reveal human off-targets of fluoroquinolone induced mitochondrial toxicity
Fluoroquinolones (FQs) are an important class of potent broad-spectrum antibiotics. However, their general use is more and more limited by adverse side effects. While general mechanisms for the Fluoroquinolone-associated disability (FQAD) have been identified, the underlying molecular origins of tox...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD047056 | Pride
Fluoroquinolones Side-effects Off-targets Chemical proteomics Proteomics Antibiotics 
ProteomicsChemical proteomics reveal human off-targets of fluoroquinolone induced mitochondrial toxicity
Fluoroquinolones (FQs) are an important class of potent broad-spectrum antibiotics. However, their general use is more and more limited by adverse side effects. While general mechanisms for the Fluoroquinolone-associated disability (FQAD) have been identified, the underlying molecular origins of tox...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056813 | Pride
Human Full proteome Timstof pro 
GenomicsWhole-genome sequencing analysis of low-grade astrocytomas within the ICGC PedBrain Tumor Project
In order to investigate the full range of genetic alterations contributing to the tumourigenesis of low-grade astrocytoma, we have conducted a next-generation sequencing-based analysis on a large series of matched tumor-normal pairs. This study, conducted by the International Cancer Genome Consortiu...
EGAS00001000381 | EGA
GenomicsDATA_SET_ICGC_PedBrain_Tumor_Low-Grade_Astrocytoma_Study - samples
Pilot study Pilocytic Astrocytoma ICGC PedBrain, whole genome sequencing of 5 tumors and matched blood
EGAD00001000271 | EGA
GenomicsICGC PedBrain: Deep-sequencing of childhood brain tumors.
Brain tumors constitute the childhood tumors with the highest mortality rates and survival is often associated with severe long-term sequelae due to intensive multimodal treatment regimens. Thus, the PedBrainTumor network aims at the identification of robust biomarkers for clinical management and no...
EGAS00001000215 | EGA
GenomicsRNA-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain RNA sequencing
EGAD00001000617 | EGA
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
GenomicsWGS-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain whole genome sequencing
EGAD00001000616 | EGA
GenomicsSHH medulloblastoma samples
Sequencing data of human SHH medulloblastoma samples
EGAS00001000607 | EGA
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