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ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
TranscriptomicsRole of NFBD1 in global gene expression
NFBD1 (nuclear factor with BRCT domains 1), also known as MDC1 (mediator of DNA damage signaling 1), is a protein involved in the ATM signaling pathway in response to DNA damage. In addition to a role in signaling, NFBD1 possesses transactivation activity, suggesting that it may influence transcrip...
ORGANISM(S): Homo sapiens 
2011-06-16 | E-GEOD-23010 | biostudies-arrayexpress
UnknownPADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation.
Not available
S-EPMC4050257 | biostudies-literature
ProteomicsHistone Modification Analysis of Oligodendroglioma and Astrocytoma Brain Cancer Samples
WHO classification for tumors of the central nervous system strongly endorses molecular tests for the precise diagnosis of diffuse gliomas. While alterations in the DNA methylation status of gliomas are already well documented and used in specialised clinical centers to distinguish between brain tum...
ORGANISM(S): Homo sapiens (Human) 
2020-01-17 | PXD015151 | Pride
Oligodendroglioma Histone modifications Brain cancer Astrocytoma Histone epi-proteome 
TranscriptomicsAnalysis of allele specific expression and its chromatin state to identify genes that are escaping X chromosome inactivation
Disappearance of the Barr body has long been considered a hallmark of cancer, although whether this corresponds to epigenetic instability and transcriptional reactivation, or to genetic loss, has remained unclear. Here we show that in breast cancer cell lines as well as primary breast tumors, the in...
ORGANISM(S): Homo sapiens 
2015-01-22 | E-GEOD-62966 | biostudies-arrayexpress
UnknownLysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability.
Not available
S-EPMC7269600 | biostudies-literature
UnknownLongitudinal Relationship of Leisure Activity Engagement With Cognitive Performance Among Non-Demented, Community-Dwelling Older Adults.
Not available
S-EPMC8963156 | biostudies-literature
UnknownRich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network.
Not available
S-EPMC4504816 | biostudies-literature
TranscriptomicsComparative genomic hybridization of human breast cancer cell lines (45) on Affymetrix 100K SNP arrays
Breast cancer cell lines grown in full serum under standard conditions were profiled on Affymetrix GeneChip Mapping 100K Set Arrays Experiment Overall Design: Profiling of cell lines grown under standard conditions
ORGANISM(S): Homo sapiens 
2009-05-01 | E-GEOD-13696 | biostudies-arrayexpress
UnknownGenome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways.
Not available
S-EPMC6787090 | biostudies-literature
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