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GenomicsSterolibacterium denitrificans strain:DSM 13999
Sterolibacterium denitrificans strain:DSM 13999 Genome sequencing and assembly
PRJNA288611 | ENA
ProteomicsRing A cleaving beta-diketon hydrolase is a key enzyme of steroid degradation in anaerobic bacteria
Bacterial degradation of the ubiquitous and persistent steroids is important for their removal from the environment, particularly for the endocrine disrupting steroid sex hormones. While aerobic bacteria use oxygenases to attack non-activated C-H/C-C bonds of the isoprenoid side chain or the steran ...
ORGANISM(S): Sterolibacterium denitrificans 
2025-05-07 | PXD053345 | Pride
Steroid degradation Lc-ms Hydrolase Sterolibacterium denitrificans 
UnknownAnoxic androgen degradation by the denitrifying bacterium Sterolibacterium denitrificans via the 2,3-seco pathway.
Not available
S-EPMC4018845 | biostudies-literature
UnknownStudy of anoxic and oxic cholesterol metabolism by Sterolibacterium denitrificans.
Not available
S-EPMC2223586 | biostudies-literature
GenomicsS_den
Genome sequence of Sterolibacterium denitrificans Chol1S
PRJEB20067 | ENA
ProteomicsWild type enrichment of a 25-phospho-steroid kinase involved in anaerobic steroid degradation
The anaerobic degradation of cholesterol fundamentally differs from the cytochrome P450 monooxygenase dependent activation of the isoprenoid side chain at C26 in aerobes. In the denitrifying β-proteobacterium Sterolibacterium denitrificans, activation of primary C26 proceeds via a three-step cascade...
ORGANISM(S): Sterolibacterium denitrificans 
2022-02-17 | PXD027031 | Pride
Cholesterol Steroid degradation Kinase 
ProteomicsBacterial stigmasterol degradation involving radical flavin delta-24 desaturase and molybdenum-dependent C26 hydroxylase
Sterols are ubiquitous membrane constituents that persist to a large extent in the environment due to their water insolubility and chemical inertness. Recently, an oxygenase-independent sterol degradation pathway was discovered in a cholesterol-grown denitrifying bacterium Sterolibacterium (S.) deni...
ORGANISM(S): Sterolibacterium denitrificans 
2024-05-21 | PXD048763 | Pride
Anaerobic metabolism Molybdenum enzyme Steroid degradation Flavin radical enzyme Stigmasterol Desaturasem 
Unknown1,2-Hydrogenation and Transhydrogenation Catalyzed by 3-Ketosteroid Δ1-Dehydrogenase from Sterolibacterium denitrificans-Kinetics, Isotope Labelling and QM:MM Modelling Studies.
Not available
S-EPMC9736390 | biostudies-literature
UnknownStructure, Mutagenesis, and QM:MM Modeling of 3-Ketosteroid Δ1-Dehydrogenase from Sterolibacterium denitrificans─The Role of a New Putative Membrane-Associated Domain and Proton-Relay System in Catalysis.
Not available
S-EPMC9960185 | biostudies-literature
UnknownBacterial stigmasterol degradation involving radical flavin delta-24 desaturase and molybdenum-dependent C26 hydroxylase.
Not available
S-EPMC11061730 | biostudies-literature
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