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GenomicsHLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans
Based on the prior knowledge of involvement of the human leukocyte antigen locus in Han Chinese patients with carbamazepine-induced Stevens-Johnson syndrome, we imputed the HLA types for each case and control subject from the array of SNPs in the Human610-Quad GWAS platform (NCBI Build 36.1). We the...
EGAS00000000036 | EGA
UnknownNeeds of family caregivers of hospitalised adults with dementia during care transitions: a qualitative study in a US Department of Veterans Affairs Hospital.
Not available
S-EPMC11340712 | biostudies-literature
ProteomicsCarbamazepine Activates Private Self and Viral Reactive TCRs Through a Drug-Permissive HLA-B Cleft
Carbamazepine (CBZ) can cause severe cutaneous adverse reactions, including Stevens-Johnson syndrome/toxic epidermal necrolysis, and is strongly associated with HLA risk alleles. However, HLA genotype alone incompletely predicts clinical risk. Adverse drug reactions depend on drug-peptide-HLA confor...
ORGANISM(S): Homo sapiens (Human) 
2026-08-18 | PXD082505 | Pride
Hla-b*57:01 Hla-b*58:01 Stevens-johnson syndrome Immunopeptidomics Hla-b*15:02 T-cell receptor Toxic epidermal necrolysis Carbamazepine 
UnknownProspective, observational study of pain and analgesic prescribing in medical oncology outpatients with breast, colorectal, lung, or prostate cancer.
Not available
S-EPMC3383175 | biostudies-literature
UnknownClinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing: 2020 Update.
Not available
S-EPMC7831382 | biostudies-literature
TranscriptomicsTranscriptome response of Methanobrevibacter ruminantium to lauric acid in cell culture.
Medium chain fatty acids (MCFA) have been shown to inhibit methanogenesis, disrupt the cell envelope, and decrease survival of Methanobrevibacter ruminantium M1 in a dose-, time-, and protonation level dependent way. However, the exact mechanisms behind these observations are still unknown. Althoug...
ORGANISM(S): Methanobrevibacter ruminantium 
2016-06-01 | E-GEOD-81199 | biostudies-arrayexpress
UnknownRandomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597.
Not available
S-EPMC3821010 | biostudies-literature
UnknownBundled Consent in US Intensive Care Units.
Not available
S-EPMC7565087 | biostudies-literature
TranscriptomicsMapping of variable DNA methylation across multiple cell types defines a dynamic regulatory landscape of the human genome
DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Many studies have mapped DNA methylation changes associated with embryogenesis, cell differentiation and cancer at a genome-wide scale. Our understanding of genome-wide DNA methylation changes...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-69894 | biostudies-arrayexpress
UnknownSite-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: protein carbonylation is diminished by ascorbic acid.
Not available
S-EPMC2825578 | biostudies-literature
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