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TranscriptomicsEffects of 20 months Dietary Methionine Restriction on Gene Expression in inguinal white adipose tissue of Fischer 344 Rats
Dietary methionine restriction (MR) has been shown to increase lifespan and decrease adiposity in rodents. This study was designed to examine the transcriptional effects of MR in metabolically relevant tissues. This experiment contains data from the inguinal white adipose tissue (IWAT). We analyzed...
ORGANISM(S): Rattus norvegicus 
2013-07-01 | E-GEOD-28599 | biostudies-arrayexpress
TranscriptomicsIdentifying molecular mechanisms of neural crest (NC) EMT and cell migration
Purpose: To identify differntially expressed transcripts in TP-0903 treated embryos that impair cranila NC EMT and cell migration in zebrafish embryos Methods: zebrafish embryos treated at 13 hpf with 5-7uM TP-0903 and DMSO for 1-, 4- and 8-hrs at 28°C. 35 embryos were collected for each treatment....
ORGANISM(S): Danio rerio 
2016-02-18 | E-GEOD-72322 | biostudies-arrayexpress
UnknownThe Effects of 1 Egg per Day on Iron and Anemia Status among Young Malawian Children: A Secondary Analysis of a Randomized Controlled Trial.
Not available
S-EPMC9213210 | biostudies-literature
MetabolomicsFuel for the Damage Induced"""": Untargeted Metabolomics in Elite Rugby Union Match Play
The metabolic perturbations caused by competitive rugby are not well characterized. Our aim is to utilize untargeted metabolomics to develop appropriate interventions, based on the metabolic fluctuations that occur in response to this collision-based team sport. Seven members of an English Premiersh...
2021-09-06 | MTBLS2967 | MetaboLights
UnknownVitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study.
Not available
S-EPMC8728359 | biostudies-literature
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
UnknownLoss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C.
Not available
S-EPMC6918596 | biostudies-literature
MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
TranscriptomicsD-2-Hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice
Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) have been discovered in several cancer types and cause the neurometabolic syndrome D2-Hydroxyglutaric aciduria (D2HGA). The mutant enzymes exhibit neomorphic activity resulting in production of D2- hydroxyglutaric acid (D-2HG). To study the pat...
ORGANISM(S): Mus musculus 
2014-03-01 | E-GEOD-54838 | biostudies-arrayexpress
TranscriptomicsDissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays
Regulation of the expression of heat-shock proteins plays an important role in the pathogenesis of Mycobacterium tuberculosis. The heat-shock response of bacteria involves genome-wide changes in gene expression. A combination of targeted mutagenesis and whole-genome expression profiling was used to ...
ORGANISM(S): Mycobacterium tuberculosis 
2007-03-07 | E-BUGS-2 | biostudies-arrayexpress
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