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GenomicsThe Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions [Mnase-seq]
The Scc2/Scc4 complex binds to broad nucleosome-free regions in the promoters of highly expressed genes. The cohesin loader is recruited to these sites by the RSC chromatin remodeling complex MNase digestion of purified DNA followed by paired-end sequencing was performed in order to investigate geno...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-56992 | biostudies-arrayexpress
UnknownAdverse childhood experiences and adolescent drug use in the UK: The moderating role of socioeconomic position and ethnicity.
Not available
S-EPMC9207135 | biostudies-literature
GenomicsMutations in histone and other genes in MLL2-impaired human and mouse cells
We used human or mouse MLL2-impaired cells (including a human DSET MLL2 cell line,) as well as their parental controls, and measured mutations in histones and a few other genes that were affected in our gH2AX ChIP-Seq experiments. We found that cells lacking or having impaired MLL2 were presenting s...
ORGANISM(S): Mus musculus 
2016-04-13 | E-GEOD-73128 | biostudies-arrayexpress
TranscriptomicsPhevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression
Staphylococcus aureus produces the cyclic dipeptides tyrvalin and phevalin (aureusimine A and B, respectively). A previous study reported that S. aureus mutants not capable of producing these compounds were less virulent in vivo through the deranged regulation of virulence factor genes. These findin...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-32920 | biostudies-arrayexpress
UnknownReasons for intending to accept or decline kidney cancer screening: thematic analysis of free text from an online survey.
Not available
S-EPMC8137225 | biostudies-literature
UnknownCardiac catheterisation: radiation doses and lifetime risk of malignancy.
Not available
S-EPMC1861453 | biostudies-literature
UnknownStructural basis for polyadenosine-RNA binding by Nab2 Zn fingers and its function in mRNA nuclear export.
Not available
S-EPMC3384006 | biostudies-literature
TranscriptomicsExpression Profiling of a Genetic Animal Model of Depression
Expression Profiling of a Genetic Animal Model of Depression Reveals Novel Molecular Pathways Underlying Depressive-like Behaviours In this study we have used genome-wide microarray expression profiling of the hippocampus and prefrontal/frontal cortex of Flinders Depression Sensitive (FSL) and cont...
ORGANISM(S): Rattus norvegicus 
2010-04-01 | E-GEOD-20388 | biostudies-arrayexpress
UnknownThermal stability of functionalized carbon nanotubes studied by in-situ transmission electron microscopy.
Not available
S-EPMC3182121 | biostudies-literature
UnknownThe COLO-COHORT (Colorectal Cancer Cohort) study: Protocol for a multi-centre, observational research study and development of a consent-for-contact research platform.
Not available
S-EPMC9796014 | biostudies-literature
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