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ProteomicsModular Vinyl-Phosphonamidates for Cysteine Directed Protein Targeting
Covalent inhibitors and chemical probes targeting ligandable cysteine residues have emerged as powerful tools in drug discovery and proteomics. In this study, we introduce vinyl-phosphonamidates (VPAs) as a novel class of latent cysteine electrophiles and assess their reactivity, selectivity, and po...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD064073 | Pride
Chemoproteomics Covalent inhibitors 
UnknownCrystal structure of the response regulator 02 receiver domain, the essential YycF two-component system of Streptococcus pneumoniae in both complexed and native states.
Not available
S-EPMC387779 | biostudies-literature
UnknownBluetooth-sensed social presence is associated with immediate vigor and delayed fatigue: A multi-method time series analysis.
Not available
S-EPMC12179627 | biostudies-literature
UnknownA plausible model of phyllotaxis.
Not available
S-EPMC1345713 | biostudies-literature
UnknownFace-to-face more important than digital communication for mental health during the pandemic.
Not available
S-EPMC10191089 | biostudies-literature
ProteomicsOptimized fragmentation improves the identification of peptides cross-linked using MS-cleavable reagents
Cross-linking mass spectrometry (XLMS) is becoming increasingly popular, and current advances are widening the applicability of the technique so that it can be utilized by non-specialist laboratories. Specifically, the use of novel mass spectrometry-cleavable (MS-cleavable) reagents dramatically red...
ORGANISM(S): Bos taurus (Bovine) Cicer arietinum (Chickpea) (Garbanzo) Streptococcus pyogenes serotype M2 Candida albicans (Yeast) Homo sapiens (Human) Oryctolagus cuniculus (Rabbit) Escherichia coli Equus caballus (Horse) 
2019-02-01 | PXD011861 | Pride
Xlms Cross-linking Cleavable cross-linking reagents Dsso Stepped-hcd 
UnknownExamining terror management theory in Ukraine: impact of air-raid alarms and explosions on mental health, somatic symptoms, and well-being.
Not available
S-EPMC10644072 | biostudies-literature
UnknownLaughter in everyday life: an event-based experience sampling method study using wrist-worn wearables.
Not available
S-EPMC11096579 | biostudies-literature
UnknownRole of the phosphatase PTEN in early vascular remodeling.
Not available
S-EPMC3606387 | biostudies-literature
UnknownLong-Term Porcine Retina Explants as an Alternative to In Vivo Experimentation.
Not available
S-EPMC10941994 | biostudies-literature
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