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UnknownTumor-infiltrating Tim-3+ T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk.
Not available
S-EPMC5087305 | biostudies-literature
TranscriptomicsHuman regulatory memory B cells defined by expression of TIM-1 and TIGIT are dysfunctional in Multiple Sclerosis.
Regulatory B cells (Bregs) play a pivotal role in suppressing immune responses, yet there is still a lack of cell surface markers that can rigorously identify them. In mouse models for multiple sclerosis (MS), TIM-1 or TIGIT expression on B cells is required for maintaining self-tolerance and regula...
ORGANISM(S): Homo sapiens 
2024-05-31 | GSE261258 | GEO
UnknownTim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD132.
Not available
S-EPMC9098864 | biostudies-literature
UnknownTim-3 downregulation by Toxoplasma gondii infection contributes to decidual dendritic cell dysfunction.
Not available
S-EPMC9615254 | biostudies-literature
UnknownTim-3 finds its place in the cancer immunotherapy landscape.
Not available
S-EPMC7326247 | biostudies-literature
UnknownThe costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse.
Not available
S-EPMC9741863 | biostudies-literature
UnknownHuman regulatory memory B cells defined by expression of TIM-1 and TIGIT are dysfunctional in multiple sclerosis.
Not available
S-EPMC11091236 | biostudies-literature
GenomicsHuman regulatory memory B cells defined by expression of TIM-1 and TIGIT are dysfunctional in Multiple Sclerosis.
Human regulatory memory B cells defined by expression of TIM-1 and TIGIT are dysfunctional in Multiple Sclerosis.
PRJNA1086179 | ENA
UnknownTim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway.
Not available
S-EPMC6479760 | biostudies-literature
UnknownThe Role of TIM-3 in Hepatocellular Carcinoma: A Promising Target for Immunotherapy?
Not available
S-EPMC7793963 | biostudies-literature
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