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This quantitative protepomics study (TMT10 isobaric labeling) of the protein expression in the retina of Msi1/Msi2 double knockout mouse compared to floxed controls. The Msi1 and Msi2 genes were knocked out in photoreceptor cells using tamoxifen inducible Cre (Cre-ERT2) under the control of Pde6g pr...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-10 | PXD030748 | Pride
We describe a method, MADS (Microarray Analysis of Differential Splicing), for discovery of differential alternative splicing from exon tiling microarrays. MADS incorporates a series of low-level analysis algorithms motivated by the “probe-rich” design of exon arrays, including background correction...
ORGANISM(S): Mus musculus 
We treated HEK293 cells with the cardiotonic steroid digitoxin to identify alternative splicing changes as compared to DMSO treatment alone. In this set, 6 total samples were analyzed. There were three biological replicates for each of two conditions: DMSO treatment and Digitoxin treatment. Arrays...
ORGANISM(S): Homo sapiens 
We have independently knocked down TRA2B and SRSF3 in HEK293 cells to identify the sum of alternative splicing changes that results from depletion of each factor. Each was compared to a control transfection of the hairpin vector alone. In this set, 9 total samples were analyzed. There were three b...
ORGANISM(S): Homo sapiens 
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