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TranscriptomicsOverexpression of Musashi1 (Msi1) in HEK293T cells.
Gene expression analysis of the Msi1 overexpression in HEK 293T cells. There were two biological replicates of Msi1 and GFP (Green Fluorescent Protein) as control, used in the experiment. Each slide includes 4 microarrays with one biological sample versus control. Samples were hybridized with dye-...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-13215 | biostudies-arrayexpress
ProteomicsThe role of Tau regulating MSI1 interactome
This project is to identify the MSI protein interaction networks and the role of Tau in regulating MSI1 protein interaction netowrk
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD049253 | Pride
Mass spectrometry Ppi Msi1 
TranscriptomicsThe RNA-binding protein Musashi1 is a central regulator of adhesion pathways in glioblastoma
The conserved RNA-binding protein Musashi1 (MSI1) has emerged as a key oncogenic factor in numerous solid tumors, including glioblastoma. However, its mechanism of action has not yet been established comprehensively. We set out to map its impact on the transcriptome in U251 cells using RNA-seq and i...
ORGANISM(S): Homo sapiens 
2015-06-29 | E-GEOD-68800 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and transgenic msi1-tap1 plants at two time points at the age of 8 days
Wild type and transgenic msi1-tap1 plants were grown and gene expression was compared at two time points at the age of 8 days.
ORGANISM(S): Arabidopsis thaliana 
2006-12-10 | E-MEXP-513 | biostudies-arrayexpress
TranscriptomicsMsi1 integrates APC loss and mTORC1 activation to promote intestinal stem cell transformation
Loss of the APC tumor suppressor in the intestinal epithelium initiates the majority of human colorectal adenocarcinomas. Constitutive β-catenin activation is thought to underlie tumorigenesis induced by loss of APC, however β-catenin activation alone does not recapitulate all APC-loss phenotypes,...
ORGANISM(S): Mus musculus 
2015-10-22 | E-GEOD-54598 | biostudies-arrayexpress
GenomicsmRNAseq in control(WT) and Msi1 KO
mRNAseq in control(WT) and Msi1 KO
PRJNA539864 | ENA
ProteomicsMouse retina from Msi1/Msi2 double knockout in photoreceptor cells
This quantitative protepomics study (TMT10 isobaric labeling) of the protein expression in the retina of Msi1/Msi2 double knockout mouse compared to floxed controls. The Msi1 and Msi2 genes were knocked out in photoreceptor cells using tamoxifen inducible Cre (Cre-ERT2) under the control of Pde6g pr...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-10 | PXD030748 | Pride
Knockout Photorecptor Mouse Msi2 Msi1 Retina 
OtherMsi1 assists CPEB1-driven polyadenylation [Msi1 RIP]
The translational reactivation of maternal mRNAs encoding the drivers of vertebrate meiosis is accomplished mainly by cytoplasmic polyadenylation. The Cytoplasmic Polyadenylation Elements (CPEs) present in the 3’ UTR of these transcripts, together with their cognate CPE-binding proteins (CPEBs), def...
ORGANISM(S): Xenopus laevis 
2017-07-17 | GSE68097 | GEO
UnknownArabidopsis MSI1 connects LHP1 to PRC2 complexes.
Not available
S-EPMC3715863 | biostudies-literature
UnknownFunctional Polymorphism in the MSI1 Gene Promoter Confers a Decreased Risk of Lung Cancer in Chinese by Reducing MSI1 Expression.
Not available
S-EPMC6030856 | biostudies-literature
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