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To predict the progression risk of non-invasive gland-forming gastric neoplasms to invasive carcinoma, we assessed lineage continuity or discontinuity between the non-invasive and invasive neoplasms by applying hierarchical clustering analysis to the gene copy-number profiles of individual tumours. ...
ORGANISM(S): Homo sapiens 
MicroRNA (miRNA) expression profiles for gastric cancers were examined to investigate the miRNA involvement in stomach carcinogenesis. miRNA microarray analysis identified statistical unique profiles, which could discriminate stomach cancers from noncancerous stomach tissues.
ORGANISM(S): Homo sapiens 
Gastric cancers account for the fourth most frequent cancer death worldwide. Although many differential gene expression profiles are reported for gastric cancers, their variation at the post-transcriptional level has not been provided yet. In this study, we compared the gene expressions of normal st...
ORGANISM(S): Homo sapiens 
Analysis of global gene expression in the antral portion of the stomach in control and mice with a developing tumor to get further insight into the exact tumor type and the influence of local gene expression. Total RNA obtained from tissue samples from the antrum. Follow up of gene expression over ...
ORGANISM(S): Mus musculus 
Reference Proteome-Based Stomach Cancer Quantitative Proteome Analysis
ORGANISM(S): Homo Sapiens (human) 
BACKGROUND & AIMS: Gastric cancer is the second most frequent cause of death from cancer in the world, diffuse-type gastric cancer (DGC) exhibiting a poor prognosis. Germline mutations of CDH1, encoding E-cadherin, have been reported in hereditary DGCs, and genetic and/or epigenetic alterations of C...
ORGANISM(S): Mus musculus 
A microarray expression profiling of stomach cancer, gastritis and normal samples reveals that microRNAs regulated by E2F1 affect TGFb-dependent cell cycle arrest and apoptosis.
ORGANISM(S): Homo sapiens 
Seven novel and potent Raf small molecule kinase inhibitors were evaluated in 7-day oral repeat-dose rat toxicity studies. All compounds tested induced hyperplasia in multiple tissues. Microarrays were used to investigate transciptional changes associated by treatment with a single compound to gain ...
ORGANISM(S): Rattus norvegicus 
Gastric cancer is still one of the most common causes of cancer-related death worldwide, which is mainly attributable to late diagnosis and poor treatment options. Infection with H. pylori, different environmental factors and genetic alterations are known to influence the risk of developing gastric ...
ORGANISM(S): Homo sapiens 
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