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In this study, we used an interdisciplinary approach, combining biophysics and systems biology, to design a microfluidic chip for the multiplexed detection and separation of pathogen cells from immune cells combined with proteomic profiling using mass spectrometry. Our nanochip design includes preci...
ORGANISM(S): Klebsiella pneumoniae subsp. pneumoniae 
2026-03-21 | PXD058426 | Pride
Cancer cell extravasation is a key step of the metastatic cascade and an attractive therapeutic opportunity. Early steps in cancer cell extravasation require formation of tentacle-like protrusions called invadopodia that physically breach the endothelial barrier and degrade extracellular matrix (EC...
ORGANISM(S): Homo sapiens (Human) 
2025-03-28 | PXD039276 | Pride
Adhesion of Staphylococcus aureus to the host’s skin and mucosae enables asymptomatic colonization and the establishment of infections. This process is facilitated by cell wall-anchored (CWA) adhesins that are covalently attached to the bacterial cell wall and exhibit affinity for host ligands. To g...
ORGANISM(S): Staphylococcus aureus 
2023-03-04 | PXD018514 | Pride
Perennial ryegrass (Lolium perenne L.) is the most cultivated cool-season grass worldwide with crucial roles in carbon fixation and fodder for livestock. Protection of these grasses from biotic and abiotic factors are dictated through a mutually-beneficial relationship with endophytes that confer bi...
ORGANISM(S): Lolium perenne subsp. perenne Epichloe festucae E2368 
2021-02-12 | PXD017961 | Pride
Plants transformed via agroinfiltration using a modified strain of Agrobacterium tumefaciens can produce antibody proteins for purification and application in antibody-based therapeutics. The preparation of large quantities of plants for transformation may require bacterial exposure to agroinfiltrat...
ORGANISM(S): Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter) 
2020-12-10 | PXD018405 | Pride
WTCCC2 project samples from Ankylosing spondylitis Cohort
The aim of this study was to identify genes associated with ankylosing spondylitis susceptibility in British and Australian individuals of European descent.
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