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ProteomicsHigh Field Asymmetric Waveform Ion Mobility Spectrometry- Mass Spectrometry to Enhance Cardiac Muscle Proteome Coverage
Heart tissue sample preparation for mass spectrometry (MS) analysis that includes pre-fractionation reduces the cellular protein dynamic range and increases the relative abundance of non-sarcomeric proteins. We previously described “IN-Sequence” (IN-Seq) where heart tissue lysate is sequentially par...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD039174 | Pride
Faims Dia-ms Cardiac In-seq 
ProteomicsHuman limbal epithelial cell-derived exosomes cargo profile and their regulatory roles in limbal stromal cells in diabetic and non-diabetic cornea
Limbal stem cells including epithelial and stromal/Mesenchymal stem cells that contribute to sustained corneal homeostasis, maintain their ability to act as self-renewal progenitor cells by virtue of their limbal niche and intercellular communication. Extracellular vehicles (EVs), including exosomes...
ORGANISM(S): Homo sapiens (Human) 
2023-10-23 | PXD040918 | Pride
Diabetes Cornea Exosomes 
ProteomicsFunctional Assessment of US SARS-CoV-2 L452R Epsilon Variant
The multiple mutations comprising the epsilon variant demonstrates the independent convergent evolution of SARS-CoV-2 with its spike protein mutation L452R also present in the delta variant. Cells infected with live viral samples of the epsilon viral variant compared to non-epsilon variant displa...
ORGANISM(S): Chlorocebus sabaeus 
2022-05-06 | PXD027995 | Pride
Faims Covid19 Vero 
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