Stress granules

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Unknown (1353)
Genomics (264)
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Other (41)
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Organisms

Homo sapiens (139)
Mus musculus (69)
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Schizosaccharomyces pombe (4)
Escherichia coli str. K-12 substr. MG1655 (3)
Zea mays (3)
Medicago truncatula (2)
Plasmodium yoelii yoelii 17XNL (2)
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Drosophila melanogaster (2)
Oryza sativa (2)
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Trypanosoma brucei (1)
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Escherichia coli K-12 (1)
Escherichia coli (1)
Homo (1)
Sus scrofa (1)
Rattus norvegicus (1)

Organisms

Homo sapiens (101)
Mus musculus (51)
Caenorhabditis elegans (10)
Saccharomyces cerevisiae (10)
Arabidopsis thaliana (8)
Escherichia coli str. K-12 substr. MG1655 (3)
Triticum aestivum (3)
Acinetobacter bohemicus (2)
Porcine epidemic diarrhea virus (2)
Drosophila melanogaster (2)
Leucobacter sp. TV5 (1)
Glutamicibacter sp. LMG 31309 (1)
Plasmodium yoelii yoelii 17XNL (1)
Lupinus angustifolius (1)
Cryptococcus neoformans H99 (1)
Brevundimonas diminuta (1)
Schizosaccharomyces pombe (1)
Homo (1)
Escherichia coli K-12 (1)
Zea mays (1)
Sus scrofa (1)
feces metagenome (1)
Nicotiana benthamiana (1)

Repository

ENA (251)
geo (208)
pride (130)
biostudies-arrayexpress (43)
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Tissue

Cell culture (33)
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HeLa cell (5)
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Leaf (2)
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Midbrain dopaminergic neuron (2)
Primary cell (2)
Root (2)
SVGp12 cell (2)
Substantia nigra (2)
A-549 cell (1)
B cell (1)
Blood (1)
Bone marrow-derived macrophage (1)
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Cell line cell (1)
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T cell (1)
U2-OS cell (1)

Disease

Disease free (5)
Amyotrophic lateral sclerosis (4)
Cerebrovascular disease (3)
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Ileus in patients with colrectal cancer after surgery (1)
Acute leukemia (1)
COVID-19 (1)
FTDALS1 (1)
Lewy body dementia (1)
Melanoma (1)
Mixed disorder as reaction to stress (1)
Myopathy (1)
Neuronal ceroid lipofuscinosis 7 (1)
Pancreatic cancer (1)
Prostate adenocarcinoma (1)
Trypanosomiasis (1)

Technology Type

Mass Spectrometry (130)
Shotgun proteomics (58)
Affinity purification coupled with mass spectrometry proteomics (32)
Bottom-up proteomics (28)
Data-dependent acquisition (18)
Gel-based experiment (8)
Top-down proteomics (6)
Data-independent acquisition (5)
Mass spectrometry (3)
Chemical cross-linking coupled with mass spectrometry proteomics (3)
DiaPASEF (3)
SWATH MS (3)
Mass spectrometry assay (2)
Affinity proteomics (2)
SRM/MRM (2)
Metaproteomics (1)
Proteogenomics (1)

Instrument Platform

Orbitrap Fusion Lumos (8)
LTQ Orbitrap Elite (6)
TripleTOF 5600 (6)
Orbitrap Exploris 480 (5)
Orbitrap Fusion (4)
LTQ Velos (3)
Illumina NovaSeq X (2)
LTQ Orbitrap Velos (2)
Q Exactive (2)
TripleTOF 6600 (2)
Liquid Chromatography MS - positive - reverse-phase (2)
G2565AA DNA microarray scanner [Agilent] (1)
Axon- GenePix4000B (1)
ScanArray 4000XL [PerkinElmer] (1)
NA (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
LTQ (1)
Orbitrap Fusion ETD (1)
Q Exactive HF (1)
Q Exactive HF-X (1)
Thermo Q Exactive HF (1)
TimsTOF Pro (1)
Liquid Chromatography MS - (1)
Liquid Chromatography MS - negative (1)
Liquid Chromatography MS - positive (1)
Liquid Chromatography MS - negative - HILIC (1)
Liquid Chromatography MS - negative - reverse-phase (1)

Publication Date

2025 (81)
2024 (77)
2023 (44)
2026 (36)
2022 (35)
2021 (25)
2017 (24)
2020 (23)
2018 (18)
2019 (17)
2016 (17)
2015 (13)
2014 (11)
2010 (5)
2013 (4)
2012 (4)
2008 (3)
2011 (2)
2009 (2)
2007 (2)
2006 (2)
2005 (2)

CHEBI ID

CHEBI:81750 (1)
CHEBI:229940 (1)
CHEBI:174326 (1)
CHEBI:39745 (1)
CHEBI:192883 (1)
CHEBI:174685 (1)
CHEBI:184259 (1)
CHEBI:89232 (1)
CHEBI:229945 (1)
CHEBI:141366 (1)
CHEBI:170316 (1)
CHEBI:190161 (1)
CHEBI:173805 (1)
CHEBI:171829 (1)
CHEBI:89506 (1)
CHEBI:190154 (1)
CHEBI:173482 (1)
CHEBI:88859 (1)
CHEBI:89500 (1)
CHEBI:192200 (1)
CHEBI:190153 (1)
CHEBI:171009 (1)
CHEBI:89977 (1)
CHEBI:190167 (1)
CHEBI:89403 (1)
CHEBI:89928 (1)
CHEBI:171363 (1)
CHEBI:184279 (1)
CHEBI:89926 (1)
CHEBI:170854 (1)

Metabolite Name

Allantoin (3)
Sebacic acid (3)
Azelaic acid (3)
Uridine (3)
Pseudouridine (3)
Hippuric acid (3)
P-Toluenesulfonic acid (2)
2-Ketohexanoic acid (2)
D-Glucuronic acid (2)
N-Acetyl-L-methionine (2)
Oxoglutaric acid (2)
Phenobarbital (2)
2-Ketobutyric acid (2)
Isovalerylglycine (2)
Pentadecanoic acid (2)
2-Hydroxy-3-methylbutyric acid (2)
4-Nitrophenol (2)
Uracil (2)
Cinnamoylglycine (2)
Pyroglutamic acid (2)
Orotic acid (2)
Indoxyl sulfate (2)
2-Isopropylmalic acid (2)
4-Pyridoxic acid (2)
Nicotinic acid (2)
Kynurenic acid (2)
Phenyllactic acid (2)
Benzoic acid (2)
Indole-3-carboxylic acid (2)
Maleic acid (2)

First Public Date

2024 (55)
2025 (43)
2026 (33)
2023 (22)
2022 (19)
2021 (16)
2016 (14)
2018 (9)
2017 (9)
2020 (8)
2019 (8)
2014 (7)
2015 (5)
2013 (3)

Modelling Approach

Mathematical model (1)
Ordinary differential equation model (1)

Study status

Completed (1)

Lab affiliation

Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg im Breisgau, Germany (5)
Department of Cell & Developmental Biology, University of California, San Diego, CA 92093, USA. (3)
Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5 (3)
First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (3)
Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany (3)
Department of Experimental Neurodegeneration, University Medical Center Goettingen (2)
Goethe University Frankfurt, University Hospital, Clinic of Neurology, Experimental Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany (2)
Institute of Biochemistry II, Goethe University, Medical School, Frankfurt, Germany (2)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (2)
School of Medicine, Sun Yat-sen University (2)
Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China (2)
State Key Laboratory for Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China (2)
University of Edinburgh (2)
1. Department of Experimental Neurodegeneration, University Medical Center Goettingen, Germany 2. 1Base Pharmaceuticals, Boston, MA 02129, USA (1)
1Centre for Bioscience, Manchester Metropolitan University, Manchester, UK (1)
Affiliation of Zhengting Chen, Jing Wang, Hebo Zhao, Yaping Yue, Biao Liu, Yu Zhao, Dao-Xiu Zhou: National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, 430070 Wuhan, China (1)
Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada (IMRIC). School of Medicine. The Hebrew University of Jerusalem, Israel. (1)
Biological and Environmental Science and Engineering Division King Abdullah University of Science and Technology (KAUST) (1)
Buchmann Institute of Molecular Life Sciences and Institute of Biophysical Chemistry, Goethe University, Frankfurt am Main, Germany (1)
CEA-Marcoule, ProGénoMIX platform, DRF-Li2D, 30207 Bagnols-sur-Cèze, France (1)
CECAD, Institute for Integrated Stress Response Signaling, Faculty of Medicine, University Hospital of Cologne (1)
CEITEC, Masaryk University Molecular medicine, RNA and immunity, CEITEC, Masaryk University (1)
Cancer Research Center of Toulouse (CRCT) 2 Avenue Hubert Curien 31037 Toulouse (1)
Cell Signaling and Clinical Proteomics Group, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo (Spain) (1)
Centre for Molecular Biology at the university Heidelberg (ZMBH), Im Neuenheimer Feld 282; 69120 Heidelberg, Germany (1)
Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus UAB, Bellaterra, Barcelona, 08193, Spain. (1)
Centro de Biología Molecular Severo Ochoa (CBMSO, CSIC-UAM). C/ Nicolás Cabrera 1. 28049 Madrid. Spain (1)
Collaborative Center for Translational Mass Spectrometry, TGen (1)
College of Life Sciences, South-Central University for Nationalities (1)
DZNE: German center for Neurodegenerative Diseases, Munich, https://www.dzne.de/index.php?id=105&L=1 (1)

IsPrivate

False (3)

Classification

bacteria (4)
viruses (2)
fungi (1)
protozoa (1)

Study type

Transcription profiling by array (25)
RNA-seq of coding RNA (9)
Unknown experiment type (2)
ChIP-chip by array (2)
Cell line - High-throughput sequencing (1)
RNAi profiling by array (1)
Other (1)
Methylation profiling by array (1)
Interventional (1)

Release Date

2023 (151)
2025 (148)
2024 (143)
2022 (141)
2021 (121)
2020 (100)
2019 (87)
2015 (67)
2018 (64)
2016 (63)
2017 (59)
2014 (46)
2013 (43)
2011 (32)
2026 (23)
2012 (23)
2010 (23)
2008 (20)
2007 (14)
2009 (11)
2006 (9)
2005 (3)
2004 (2)
2002 (1)
2000 (1)

Location

Malaysia (1)

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Biosynthesis of polyamine–polyphosphate granules for colitis alleviation

Natural polyamines, such as spermidine and spermine, exert strong anti-inflammatory effects, but their therapeutic benefits are limited by rapid absorption in the small intestine, resulting in low colonic availability. In this study, engineered Citrobacter freundii overexpressing ppk1 (CPP) coul...

2026-01-07 | MTBLS13621 | MetaboLights

PKA regulates stress granule maturation to allow timely recovery after prolonged starvation

Cells have evolved multiple strategies to survive environmental stress conditions. This includes the formation of membrane-less cytoplasmic ribonucleoprotein structures called stress granules that sequester and protect mRNAs encoding many housekeeping genes. Stress granules are not static biomolecul...

2026-06-16 | MTBLS13923 | MetaboLights

RNA localization to stress granules

PRJNA875210 | ENA

RIOK1 Phase Separation Shapes Stress Adaptation and Cell Fate in Hepatocellular Carcinoma

Cancer cells can always be unexpected rescued from desperate environment by mounting adaptive responses to resolve the arising cellular stress. The dynamic stress granules (SGs) assembly and metabolic reprogramming play crucial roles in maintaining cellular growth and homeostasis. However, the me...

2025-02-26 | MTBLS11963 | MetaboLights

ECT2 and AURKB Modulate Formation of Stress Granules Containing Transcripts from Diverse Cellular Pathways in Astrocytoma Cells

Stress granules are small RNA-protein granules that modify the translational landscape during cellular stress to promote survival. The RhoGTPase RhoA is implicated in the formation of RNA stress granules. Our data demonstrate that the cytokinetic proteins ECT2 and AurkB are localized to stress gran...

ORGANISM(S): Homo sapiens

2016-02-29 | E-GEOD-76814 | biostudies-arrayexpress

The stress granule transcriptome reveals principles of mRNA accumulation in stress granules.

PRJNA388080 | ENA

The Proteome and Transcriptome of Stress Granules and P-Bodies during Human T Lymphocytes Activation

Stress granules (SGs) and processing bodies (PBs) are membraneless cytoplasmic assemblies regulating mRNAs under environmental stress such as viral infections, neurological disorders, or cancer. Upon antigen stimulation, T lymphocytes mediate their immune functions under regulatory mechanisms involv...

ORGANISM(S): Homo sapiens (Human)

2023-03-10 | PXD031639 | Pride

Fasnall induces atpically transient Stress Granules

Stress Granule formation has been linked to the resistance of some cancer cells to chemotherapeutic intervention. A number of studies have proposed that certain anti-tumor compounds promote cancer cell survival by inducing Stress Granules formation, leading to increased cellular fitness and apoptosi...

ORGANISM(S): Homo sapiens (Human)

2021-09-09 | PXD021229 | Pride

Stress granule Fasnall Pabpc1

Stress Granules FUS WT e FUS P525L

Stress Granules (SG) formation is a cellular protection mechanism, constituting a storage for untranslated mRNAs and RNA-binding proteins (RBPs); however, these condensates can turn into pathological aggregates, related to the onset of neurodegenerative diseases like Amyotrophic Lateral Sclerosis (A...

ORGANISM(S): Homo sapiens (Human)

2025-05-06 | PXD049234 | Pride

Stress granules Als Rna-binding proteins Neurodegeneration Aggregation

Neuromelanin granules of the substantia nigra: proteomic profile provides links to tyrosine hydroxylase, stress granules and lysosomes

Neuromelanin is a black-brownish pigment, present in so-called neuromelanin granules (NMGs) in the cell bodies of dopaminergic neurons in the substantia nigra (SN) pars compacta. These neurons are lost in neurodegenerative diseases like Parkinson’s disease and dementia with Lewy bodies. Although it ...

ORGANISM(S): Homo sapiens (Human)

2022-08-29 | PXD033533 | Pride

Laser microdissection Stress granules Mass spectrometry Substantia nigra pars compacta Neuromelanin synthesis Neuromelanin granules

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