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A delicate balance in cellular signaling is required for plants to distinguish mutualist from parasitic organisms in its environment. Mitogen-activated protein kinase (MAPK) cascades are one of the signaling modules that mediate transduction of extracellular microbial signals into appropriate cellul...
2017-08-25 | MTBLS441 | MetaboLights

Bacteria secrete exosomes containing stress-related molecules such as proteins and nucleic acids, which facilitate adaptation to challenging environments. In order to elucidate the role of A. acidoterrestris exosomes in its acid stress response, this study combined proteomics and metabolomics to ...

2025-09-13 | MTBLS12995 | MetaboLights

Bacteria secrete exosomes containing stress-related molecules such as proteins and nucleic acids, which facilitate adaptation to challenging environments. In order to elucidate the role of A. acidoterrestris exosomes in its acid stress response, this study combined proteomics and metabolomics to ...

2025-09-14 | MTBLS12996 | MetaboLights
Nontargeted and targeted metabolomics measurements of abiotic stress responses in three-week-old Arabidopsis thaliana plants' rosette leaf tissue for Col-0 wild type plants and double/triple knockout mutants of aquaporins (pip2;1 pip2;2 and pip2;1 pip2;2 pip2;4) treated with drought, heat at differe...
2017-07-17 | MTBLS355 | MetaboLights

The scarcity of potassium resources in farmland soils poses a major challenge to global food security. Wild soybean (Glycine soja), a valuable wild germplasm related to cultivated soybeans, is known for its high-stress resistance and adaptability. This study comprehensively compares two wild soyb...

2026-04-12 | MTBLS14256 | MetaboLights
The long-term maintenance of hematopoietic stem cells (HSCs) relies on the regulation of endoplasmic reticulum (ER) stress at a low level, but the underlying mechanism remains poorly understood. Here, we demonstrate that suppression of ER stress improves the functions of HSCs and protects HSCs again...
2025-06-04 | MTBLS12489 | MetaboLights
The long-term maintenance of hematopoietic stem cells (HSCs) relies on the regulation of endoplasmic reticulum (ER) stress at a low level, but the underlying mechanism remains poorly understood. Here, we demonstrate that suppression of ER stress improves the functions of HSCs and protects HSCs again...
2025-06-04 | MTBLS12491 | MetaboLights
BACKGROUND: Plants respond to various stress stimuli by activating an enhanced broad-spectrum defensive ability. The development of novel resistance inducers represents an attractive, alternative crop protection strategy. In this regard, hexanoic acid (Hxa, a chemical elicitor) and azelaic acid (Aza...
2018-10-17 | MTBLS559 | MetaboLights
This model is from the article: Modelling the Role of the Hsp70/Hsp90 System in the Maintenance of Protein Homeostasis Proctor CJ, Lorimer IAJ PLoS ONE2011; 6(7): e22038. doi:10.1371/journal.pone.0022038, Abstract: Neurodegeneration is a...
2024-09-02 | BIOMD0000000344 | BioModels

Background The role of dietary interventions, particularly lysine-restricted diets(LRD), in mitigating obesity-associated anxiety-like behaviors remains poorly understood, with limited insight into gut microbiota-metabolite-brain axis mechanisms.

Results LRD significantly improved anxiety b...

2025-09-18 | MTBLS13013 | MetaboLights
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