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TranscriptomicsThe role of cytokinins in clubroot disease
Clubroot (Plasmodiophora brassicae) is a pathogen of Brassicaceae that causes significant reductions in yield as a consequence of gall formation in the root and hypocotyl of infected plants. The pathogen hijacks host vascular cambium development and cytokinins are implicated in this process. RNASeq ...
ORGANISM(S): Arabidopsis thaliana 
2016-07-04 | E-MTAB-4176 | biostudies-arrayexpress
TranscriptomicsThe Drosophila immune response towards entomopathogenic nematodes and their associated bacteria.
Entomopathogenic nematodes (EPNs) of the genera Heterorhabditis are obligate and lethal insect parasites. In recent years they have been used increasingly as biological control agents. These EPNs are symbiotically associated with bacteria of the genera Photorhabdus. The bacterial symbionts are essen...
ORGANISM(S): Drosophila melanogaster 
2014-03-07 | E-MTAB-1542 | biostudies-arrayexpress
ProteomicsBiomarkers of hepatocellular synthesis predict mortality in patients with decompensated cirrhosis
Background & Aims: Since liver hepatocytes produce the majority of serum proteins, liver cirrhosis displays a massive alteration in serum proteome. The aim of the current study was to characterize these alterations and to study the prognostic usefulness of hepatocellular proteins available in routin...
ORGANISM(S): Homo sapiens (Human) 
2023-11-20 | PXD035024 | Pride
Biomarker Serum Human Cirrhosis Lc-ms/ms 
UnknownEndocrine therapy with accelerated Partial breast irradiatiOn or exclusive ultra-accelerated Partial breast irradiation for women aged ≥ 60 years with Early-stage breast cancer (EPOPE): The rationale for a GEC-ESTRO randomized phase III-controlled trial.
Not available
S-EPMC8102143 | biostudies-literature
ProteomicsLoss of the mechanistic target of rapamycin complexes 1 (mTORC1) causes a lethal alpha-1 antitrypsin deficiency associated liver disease
Alpha1-antitrypsin (AAT) mutations cause retention of the otherwise secreted protein and lead to the proteotoxic AAT deficiency (AATD)-related liver disease (AATD-LD). As mechanistic target of rapamycin (mTOR) is a key coordinator of proteostasis, we studied its role in AATD-LD. PiZ mice overexpress...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD061881 | Pride
Mouse Lc-ms Serum Liver Spatial Proteome 
TranscriptomicsDiurnal gene expression in Populus wild type and lhy RNAi line 10
Previous studies have shown that a considerable proportion of the Arabidopsis genome cycles under circadian and/or diurnal conditions (Edwards et al., 2006 PMID: 16473970, Blaesing et al., 2005 PMID 16299223). It is likely that the correct phasing of gene expression plays an important role in improv...
ORGANISM(S): Populus tremula x Populus tremuloides 
2018-03-13 | E-MTAB-4516 | biostudies-arrayexpress
TranscriptomicsEffects of Dcp1a and Dcp2 knockdown during mouse oocyte maturation
Oocyte maturation is accompanied by a transition from mRNA stability to instability. We investigated the role of DCP1A and DCP2, proteins responsible for mRNA decapping, in mRNA destabilization during mouse oocyte maturation. siRNA-mediated knockdown of both Dcp1a and Dcp2 transcripts prior to ini...
ORGANISM(S): Mus musculus 
2013-02-06 | E-GEOD-27049 | biostudies-arrayexpress
UnknownGenome Sequence of Rhodococcus erythropolis Strain CCM2595, a Phenol Derivative-Degrading Bacterium.
Not available
S-EPMC3961730 | biostudies-literature
UnknownKeratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations.
Not available
S-EPMC3249217 | biostudies-literature
TranscriptomicsTranscription profiling by array of cancer associated fibroblasts from pancreatic ductal adenocarcinoma in comparison to normal dermal fibroblasts
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor type with extremely high mortality (up to 92%) during 5 years after diagnosis. Here, cancer associated fibroblasts (CAF) from PDAC were compared to CAF from melanoma metastases (MELF) and to normal dermal fibroblasts (DF). The analysis w...
ORGANISM(S): Homo sapiens 
2021-11-01 | E-MTAB-8764 | biostudies-arrayexpress
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