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TranscriptomicsThe Drosophila immune response towards entomopathogenic nematodes and their associated bacteria.
Entomopathogenic nematodes (EPNs) of the genera Heterorhabditis are obligate and lethal insect parasites. In recent years they have been used increasingly as biological control agents. These EPNs are symbiotically associated with bacteria of the genera Photorhabdus. The bacterial symbionts are essen...
ORGANISM(S): Drosophila melanogaster 
2014-03-07 | E-MTAB-1542 | biostudies-arrayexpress
ProteomicsBiomarkers of hepatocellular synthesis predict mortality in patients with decompensated cirrhosis
Background & Aims: Since liver hepatocytes produce the majority of serum proteins, liver cirrhosis displays a massive alteration in serum proteome. The aim of the current study was to characterize these alterations and to study the prognostic usefulness of hepatocellular proteins available in routin...
ORGANISM(S): Homo sapiens (Human) 
2023-11-20 | PXD035024 | Pride
Biomarker Serum Human Cirrhosis Lc-ms/ms 
TranscriptomicsGene expression profiling in mice overexpressing human wild type (WT) keratin 8 (K8) or K8 variants (G62C and R341H).
3 months old untreated male/female animals were used in the experiment. We used microarray analysis to determine differential gene expression in mice livers overexpressing WT K8 and K8 variants. Mice liver tissues were used for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2014-08-27 | E-GEOD-60780 | biostudies-arrayexpress
TranscriptomicsExpression data from the mouse liver with constitutively active NF-kB
Activation of hepatic NF-kB signaling induces inflammation and ultimately fibrosis. To investigate the underlying mechanism, we used microarrays to detail the global programme of gene expression which is regulated by hepatic NF-kB signaling. We generated transgenic mice which express a constitutivel...
ORGANISM(S): Mus musculus 
2012-03-31 | E-GEOD-28085 | biostudies-arrayexpress
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