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UnknownStrumpellin and Spartin, Hereditary Spastic Paraplegia Proteins, are Binding Partners.
Not available
S-EPMC4426939 | biostudies-literature
UnknownThe WASH-complex subunit Strumpellin regulates integrin αIIbβ3 trafficking in murine platelets.
Not available
S-EPMC10260982 | biostudies-literature
UnknownLoss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.
Not available
S-EPMC5082549 | biostudies-literature
ProteomicsN471D WASH complex subunit strumpellin knock-in mice display BPTF and KLHL11 dysregulation in brain tissue
We investigated brain tissue from N471D WASH complex subunit strumpellin knock-in mice as a genetic model for hereditary spastic paraplegia type 8. While WASHC5-related protein interaction partners and complexes showed no change in abundancies, the proteomic analysis depicted consistent upregulation...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-26 | PXD025315 | Pride
Strumpellin  wash complex subunit 5  n451d strumpellin knock-in mice  spg8  hereditary spastic paraplegia  bptf  nurf  klhl11 Lc-msms 
UnknownExpression of N471D strumpellin leads to defects in the endolysosomal system.
Not available
S-EPMC6177004 | biostudies-literature
UnknownHereditary spastic paraplegia SPG8 mutations impair CAV1-dependent, integrin-mediated cell adhesion.
Not available
S-EPMC7231525 | biostudies-literature
UnknownWASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes.
Not available
S-EPMC4083260 | biostudies-literature
UnknownThe cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.
Not available
S-EPMC2964111 | biostudies-literature
UnknownDefects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia.
Not available
S-EPMC5412567 | biostudies-literature
UnknownFirst patient with hereditary spastic paraplegia type 8 in Poland.
Not available
S-EPMC5582219 | biostudies-literature
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