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TranscriptomicsProfiling of sex-biased expression in Drosophila species
Extensive sex-biased expression has been seen in multiple surveys D. melanogaster. We were interested in broadly sampling sex-biased expression of orthologs and species- or lineage-specific genes in the Drosophila genus. To appropriately assay gene expression in multiple species, we used custom micr...
ORGANISM(S): Drosophila melanogaster 
2007-11-07 | E-GEOD-6640 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of whole flies from Drosophila
We sequenced mRNA from whole flies of females and male of Drosophila melanogaster, D. simulans, D. yakuba, D. ananassae, D. pseudobscura, D. mojavensis, and D. virilis as part of the modENCODE project to validate novel gene models found in D. melanogaster, identify genes differentially expressed bet...
ORGANISM(S): Drosophila melanogaster 
2011-03-23 | E-GEOD-28078 | biostudies-arrayexpress
TranscriptomicsTranscriptional effects of I-PpoI induced DNA double strand breaks in mouse lymphocytes
DNA double-strand breaks (DSBs) and their repair can cause extensive epigenetic changes. As a result, DSBs have been proposed to promote transcriptional and, ultimately, physiological dysfunction via both cell-intrinsic and cell-non-autonomous pathways. Studying the consequences of DSBs in higher or...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-74855 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of head tissue from Doa and fne mutants, Drosophila melanogaster.
Transcriptional profiling of head tissue of Drosophila Darkener of apricot (Doa) and found in neurons (fne) mutants was performed by RNA-SEQ in females and males. The transcriptional and post-transcriptional targets of these genes, which are involved in regulation by several processes including spli...
ORGANISM(S): Drosophila melanogaster 
2014-03-13 | E-GEOD-37811 | biostudies-arrayexpress
GenomicsEffects of dynamic cytosine methylation on alternative pre-mRNA splicing in T lymphocytes
Intragenic 5-methylcytosine and CTCF mediate opposing affects on pre-mRNA splicing: CTCF promotes inclusion of weak upstream exons through RNA polymerase II pausing, whereas 5-methylcytosine evicts CTCF, leading to exon exclusion. However, the mechanisms governing dynamic DNA methylation at CTCF bin...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-74850 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of whole adult females and males, and miixed sex embryos, from multiple Drosophila species
We performed transcriptional profiling of sexed whole adults and mixed sex embryos of eight Drosophila species. These data were used in a comparative transcriptomics analysis of multiple Drosophila species to define functional elements conserved throughout the Drosophila genus. For each species, wi...
ORGANISM(S): Drosophila rhopaloa 
2013-02-22 | E-GEOD-43321 | biostudies-arrayexpress
TranscriptomicsIdentification of transcripts whose abundance changes in response to acute switches in DSX isoform
RNAseq of dissected adult fat body after DSX isoform is switched using temperature inducible alleles or constructs. Biological duplicates were sequenced for each genotype at each condition.
ORGANISM(S): Drosophila melanogaster 
2014-10-30 | E-GEOD-55848 | biostudies-arrayexpress
TranscriptomicsExpression profile analysis of menin1 mutants
Expression analysis of Drosophila embryos with mnn overexpression, and adults with mnn deletion. Keywords: Expression analysis Described in Cerrato et al, Dev Biol. 2006 Oct 1;298(1):59-70.
ORGANISM(S): Drosophila melanogaster 
2008-01-27 | E-GEOD-9425 | biostudies-arrayexpress
UnknownVariation in Initial U.S. Hospital Responses to the Coronavirus Disease 2019 Pandemic.
Not available
S-EPMC8217146 | biostudies-literature
GenomicsIdentifying targets of DSX with DamID-seq
We have adapted the DamID protocol for use with high throughput sequencing. We have used DamID to identify the positions within the Drosophila genome where the transcription factor DSX is bound. We sequenced DpnI-digested genomic DNA from fly tissues containing UAS-Dam (control) or UAS-Dam-DsxF or ...
ORGANISM(S): Drosophila melanogaster 
2014-10-30 | E-GEOD-27269 | biostudies-arrayexpress
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