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TranscriptomicsTranscription profiling of 4 week old BALB/c_Fech m1Pas mice (Fech) vs with 4 week old control BALB/c mice
Comparison of liver gene expression of 4 week old BALB/c_Fech m1Pas mice(Fech mice for short) with 4 week old control BALB/c mice.
ORGANISM(S): Mus musculus 
2005-10-21 | E-MEXP-194 | biostudies-arrayexpress
TranscriptomicsSequencing of HSV-1 genomic DNA to identify genomic variation resulting from selective pressure imposed by mutation of the PP1 binding site in the pUL21 gene
The pUL21 gene is essential for efficient replication and dissemination in herpes simplex virus 1 (HSV-1) but the molecular basis for its function is not well understood. Experimental work revealed that pUL21 is a virus-encoded adaptor of protein phosphatase 1 (PP1). Mutation of the specific motif i...
ORGANISM(S): Human alphaherpesvirus 1 
2021-07-31 | E-MTAB-10788 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of cultured rat primary proximal tubular cells (PTC) after isolation and differentiation
The aim of this study is to evaluate the transcripitomics changes during dedifferentiation up to 7 days in a transwell system of rat primary proximal tubular cell (PTC) cultures isolated from rat kidneys. Samples were taken from freshly isolated PTC (0 days) and at timeponts during PTC differentiati...
ORGANISM(S): Rattus norvegicus 
2024-06-30 | E-MTAB-13633 | biostudies-arrayexpress
GenomicsPS
Psoriasis cases as part of WTCCC2 phase 2
EGAD00010000124 | EGA
GenomicsGenome wide association scan in psoriasis
To identify novel susceptibility loci for psoriasis, we undertook a genome-wide association scan of of 594,224 SNPs in 2,622 individuals with psoriasis and 5,667 controls.
EGAS00000000108 | EGA
ProteomicsGlobal Enrichment of Low-Abundance Peptide Hormones in Plasma for Discovery and Quantitation
We describe a method for global enrichment of active peptide hormones from blood plasma for both new hormone discovery and quantitative analysis. To extend the dynamic range of plasma proteomics, we employed high-resolution size exclusion chromatography to purify the peptide hormones and a powerful ...
ORGANISM(S): Homo sapiens (Human) 
2019-07-16 | PXD011797 | Pride
Human  plasma  intermittent fasting  peptide hormone  insulin  hepcidin  glp-1  igf-1. 
TranscriptomicsComparative genomic hybridization of variably invasive strains of Neisseria meningitidis
Genomic comparison of more and less invasive strains of Neisseria meningitidis
ORGANISM(S): Neisseria meningitidis 
2005-05-30 | E-MEXP-343 | biostudies-arrayexpress
TranscriptomicsSpecialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary
Here, we analyzed nine Drosophila piRNA pathway mutants for their impacts on both small RNA populations and the sub-cellular localization patterns of Piwi proteins. We find that distinct piRNA pathways with differing components function in ovarian germ and somatic cells. Keywords: Epigenetics 20 li...
ORGANISM(S): Drosophila melanogaster 
2009-04-29 | E-GEOD-15186 | biostudies-arrayexpress
TranscriptomicsArctic charr exposed to acute thermal stress
Arctic charr is an especially attractive aquaculture species given that it features the desirable tissue traits of other salmonids, but can be bred and grown at inland freshwater tank farms year round. It is therefore of interest to develop upper temperature tolerant (UTT) strains of Arctic charr to...
ORGANISM(S): Salmo salar 
2011-06-01 | E-GEOD-26306 | biostudies-arrayexpress
TranscriptomicsGenome-scale transcriptomic study into the role of AbsA2 in regulating antibiotic biosynthesis in Streptomyces coelicolor
Here we report the construction of a absA2 mutant strain which exhibited the classic precocious hyper-production of antibiotics and its complementation by an N-terminal triple-FLAG tagged version of AbsA2. The complemented and non-complemented absA2 mutant strains were used in large-scale time-cours...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2019-02-16 | E-MTAB-3528 | biostudies-arrayexpress
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