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MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
ProteomicsAnalysis of the psychrophilic fungus Mrakia psychrophila using shotgun proteomics
Comprehensive and quantitative information of the psychrophile proteome is an important source for understanding of the cold adaptation mechanism under low growth temperature. Mrakia psychrophila, a obligate fungus, was selected to quantitatively evaluate its protein abundance changes in response to...
ORGANISM(S): Mrakia psychrophila 
2016-12-07 | PXD004881 | Pride
Psychrophilic Fungi Itraq 
ProteomicsProteomics revealed the crosstalk between copper stress and cuproptosis
As an essential micronutrient element in organisms, copper controls a host of fundamental cellular functions. Recently, copper-dependent cell growth and proliferation have been defined as "cuproplasia". Conversely, “cuproptosis” represents copper-dependent cell death, a nonapoptotic manner. So far, ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-17 | PXD037278 | Pride
Human Cuproptosis Copper stress Cancer 
ProteomicsProteomics explored the feasibility of curcumin as anticancer copper ionophore
As an essential micronutrient element in organisms, copper controls a host of fundamental cellular functions. Recently, copper-dependent cell growth and proliferation have been defined as "cuproplasia". Conversely, “cuproptosis” represents copper-dependent cell death, a nonapoptotic manner. So far, ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-17 | PXD037337 | Pride
Curcumin Curcumin 
TranscriptomicsTranscription profiling of pituitary glands from wild type and LSD1 knock-out mice
Precise control of transcriptional programs underlying metazoan development is modulated by enzymatically active co-regulatory complexes, coupled with epigenetic strategies, but how specific members of histone modification enzyme families such as histone methyltransferases and demethylases are utili...
ORGANISM(S): Mus musculus 
2007-02-13 | E-TABM-223 | biostudies-arrayexpress
UnknownPRV gD-Based DNA Vaccine Candidates Adjuvanted with cGAS, UniSTING, or IFN-α Enhance Protective Immunity.
Not available
S-EPMC12567548 | biostudies-literature
UnknownMatrine suppresses cell growth of diffuse large B-cell lymphoma via inhibiting CaMKIIγ/c-Myc/CDK6 signaling pathway.
Not available
S-EPMC8178855 | biostudies-literature
MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
UnknownNomogram for Predicting Semen Parameters Improvement after Microscopic Varicocelectomy in Infertile Men with Abnormal Semen Parameters.
Not available
S-EPMC9865251 | biostudies-literature
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