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MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
ProteomicsEnrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis
Chinese hamster ovary (CHO) cells have been widely employed for production of recombinant proteins (RP) for research and therapeutic purposes. Indeed, this expression system was used for production of most of approved antibodies (84%) in 2015-2018 period. The success of this cell line for RP product...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2020-08-27 | PXD019778 | Pride
Organelles Subcellular fractionation Subcellular proteomics Chinese hamster ovary cells 
UnknownProtein-retention expansion microscopy for visualizing subcellular organelles in fixed brain tissue.
Not available
S-EPMC8370715 | biostudies-literature
UnknownSubcellular Mass Spectrometry Imaging and Absolute Quantitative Analysis across Organelles.
Not available
S-EPMC7199216 | biostudies-literature
UnknownImaging trace element distributions in single organelles and subcellular features.
Not available
S-EPMC4766485 | biostudies-literature
UnknownSizing subcellular organelles and nanoparticles confined within aqueous droplets.
Not available
S-EPMC2692466 | biostudies-literature
ProteomicsPichia pastoris organelles by LC-ESI-MS
Organelles from Pichia, either grown on glucose or methanol were purified and analysed using LC-ESI-MS. Two biological replicates each had been analyzed leading to four replicate data sets for every organelle. Organelles analyzed: cis golgi, trans golgi, plasma membrane, microsomes, cytosol, vacuole...
ORGANISM(S): Komagataella pastoris (Yeast) (Pichia pastoris) 
2020-05-26 | PXD011220 | Pride
Organelle preparation Pichia pastoris 
UnknownMetabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles.
Not available
S-EPMC8552344 | biostudies-literature
UnknownDeep learning-based segmentation of subcellular organelles in high-resolution phase-contrast images.
Not available
S-EPMC11930775 | biostudies-literature
UnknownSystematic study of subcellular localization of Arabidopsis PPR proteins confirms a massive targeting to organelles.
Not available
S-EPMC3858439 | biostudies-literature
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