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MetabolomicsGrowth Substrate and Prophage Induction Collectively Influence Metabolite and Lipid Profiles in a Marine Bacterium

Bacterial growth substrates influence a variety of biological functions, including the biosynthesis and regulation of lipid intermediates. The extent of this rewiring is not well understood nor has it been considered in the context of virally-infected cells. Here, we use a one-host-two-temperate ...

2022-08-04 | MTBLS5345 | MetaboLights
MetabolomicsCoupled nitrogen fixation and substrate stabilization drive ecological strategy shifts during microbial succession

Background:

Primary succession is predicted to proceed through shifts from stress-tolerant to competitive to cooperative ecological strategies as resource availability increases, yet molecular evidence for these transitions in microbial systems remains limited. Here, we used an integrated m...

2026-03-12 | MTBLS14041 | MetaboLights
ProteomicsThe branched-chain amino acid transporter AAT10.2 of Trypanosoma brucei is regulated by substrate availability
A phosphoproteome analysis of procyclic form T. brucei revealed many amino acid transporters (AATs) of the amino acid/auxin permease (AAAP) family with phosphorylated residues exclusively in their hydrophilic N-terminal domain. AAT10.2, which contained multiple phosphorylated residues, was further c...
ORGANISM(S): Trypanosoma brucei 
2026-09-14 | PXD079824 | Pride
Phosphoproteomics Amino acid Branched-chain amino acids Transport Parasite Substrate specificity Tb927.8.8300 
GenomicsExercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability
Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability
PRJNA702786 | ENA
TranscriptomicsPhylogenetic patterns in the microbial response to resource availability: amino acid incorporation in San Francisco Bay
Aquatic microorganisms are typically identified as either oligotrophic or copiotrophic, representing trophic strategies adapted to low or high nutrient concentrations, respectively. Here, we sought to take steps towards identifying these and additional adaptations to nutrient availability with a qua...
ORGANISM(S): marine metagenome 
2014-03-26 | E-GEOD-56119 | biostudies-arrayexpress
UnknownStronger compensatory thermal adaptation of soil microbial respiration with higher substrate availability.
Not available
S-EPMC10945366 | biostudies-literature
TranscriptomicsEffect of gas-substrate limitation on barophilic growth of Methanocaldocccus jannaschii at 500 atm.
Barophilic growth of the hyperthermophilic methanarchaeon Methanocaldococcus jannaschii occurred when gas-substrate availability did not limit growth. In contrast, when growth was limited by gas transfer, no enhancement of growth was evident and a stress response was exhibited at both high and low p...
ORGANISM(S): Methanocaldococcus jannaschii 
2006-08-01 | GSE4519 | GEO
GenomicsCysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1
Cysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1
PRJNA1364011 | ENA
UnknownCartilage Redox Balance Is Influenced by Substrate Availability.
Not available
S-EPMC12449300 | biostudies-literature
UnknownEnergetic substrate availability regulates synchronous activity in an excitatory neural network.
Not available
S-EPMC6692003 | biostudies-literature
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