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ProteomicsASCL1: a pioneer factor that induces subtype switching and characterizes adrenergic neuroblastoma
Neuroblastoma is an embryonic malignancy originating from early nerve cells. Neuroblastoma retains plasticity, interconverting between the mesenchymal (MES) and adrenergic (ADRN) states, which are controlled by different sets of transcription factors forming the core regulatory circuit (CRC). Howeve...
ORGANISM(S): Homo sapiens (Human) 
2023-12-08 | PXD037670 | Pride
Ascl1 Subtype switching Neuroblastoma Pioneer factor Core regulatory circuit 
GenomicsTranscriptional control of subtype switching ensures adaptation and growth of pancreatic cancer
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer
PRJNA543003 | ENA
TranscriptomicsExpression profiling of budding cells in colorectal cancer suggests an EMT-like phenotype and molecular subtype switching
Tumour buds undergo phenotype switching while detaching from the main tumour, as they acquire more migratory characteristics and tend to stop proliferating. Simultaneously, an EMT-like signature is observed in the tumour buds under the form of active WNT, TGF and receptor tyrosine kinase signalling....
ORGANISM(S): Homo sapiens 
2017-02-04 | E-MTAB-4065 | biostudies-arrayexpress
UnknownSubtype switching in breast cancer brain metastases: a multicenter analysis.
Not available
S-EPMC7471502 | biostudies-literature
UnknownExtreme genetic divergence is required for coreceptor switching in HIV-1 subtype C.
Not available
S-EPMC3006070 | biostudies-literature
GenomicsASCL1 a pioneer factor that induces subtype switching and characterizes adrenergic neuroblastoma
ASCL1 a pioneer factor that induces subtype switching and characterizes adrenergic neuroblastoma
PRJNA887087 | ENA
GenomicsExpression profiling of budding cells in colorectal cancer suggests an EMT-like phenotype and molecular subtype switching
Expression profiling of budding cells in colorectal cancer suggests an EMT-like phenotype and molecular subtype switching
PRJEB11806 | ENA
TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
GenomicsKDM6A Epigenetically Regulates Subtype Plasticity in Small Cell Lung Cancer
KDM6A Epigenetically Regulates Subtype Plasticity in Small Cell Lung Cancer
PRJNA869671 | ENA
UnknownTranscription factor switching drives subtype-specific pancreatic cancer.
Not available
S-EPMC12695649 | biostudies-literature
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