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ProteomicsDecreased antibiotic susceptibility driven by global remodeling of the Klebsiella pneumoniae proteome
Bacteria can circumvent the effect of antibiotics by transitioning to a poorly understood physiological state that does not involve conventional genetic elements of resistance. Here we examine antibiotic susceptibility with a Class A β-lactamase+ invasive strain of Klebsiella pneumoniae that was iso...
ORGANISM(S): Klebsiella pneumoniae 
2019-03-14 | PXD010244 | Pride
Klebsiella pneumoniae proteome Antibiotics 
ProteomicsKlebsiella pneumoniae protomic response to antibiotics
Bacteria can circumvent the effect of antibiotics by transitioning to a poorly understood physiological state that does not involve conventional genetic elements of resistance. Here we examine antibiotic susceptibility with a Class A β-lactamase+ invasive strain of Klebsiella pneumoniae that was iso...
ORGANISM(S): Klebsiella pneumoniae 
2019-03-14 | PXD009175 | Pride
Doxycycline Streptomycin Klebsiella pneumoniae Lc-ms/ms 
ProteomicsProteomic perturbations of extended spectrum beta-lactamase producing Klebsiella pneumoniae by using LC MS/MS
A comprehensive analysis of proteome changes in ESBL-KP cells in response to the sub-MIC doses of antibiotics was performed by using label-free quantitative mass spectrometry.
2017-12-11 | PXD005587 | Pride
Doxycycline Streptomycin Klebsiella pneumoniae 
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