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ProteomicsSulfisoxazole inhibits exosome secretion for potential breast cancer treatment
Inhibitors of the secretion of cancer exosomes, which promote cancer progression and metastasis, can not only accelerate exosome biology research but also offer therapeutic benefits for cancer patients. We identified sulfisoxazole (SFX) which inhibits exosome secretion from breast cancer cells. SFX,...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD012689 | Pride
Breast cancer Sulfisoxazole Exosome Lc-ms/ms 
GenomicsExpression data from sulfisoxazole-treated cancer cells
Expression data from sulfisoxazole-treated cancer cells
PRJNA483940 | ENA
TranscriptomicsExpression data from sulfisoxazole-treated cancer cells
Sulfisoxazole, a FDA-approved drug, is a promising repositioned drug candidate for the treatement of various cancers. Therefore we analyzed the gene expression by microarray to identified the up-regulated and down-regulated genes after SFX treatment in both, melanoma and breast cancer cells.
ORGANISM(S): Homo sapiens 
2018-08-02 | GSE117991 | GEO
GenomicsmiRNA Expression data from sulfisoxazole-treated breast cancer cell-derived exosome
miRNA Expression data from sulfisoxazole-treated breast cancer cell-derived exosome
PRJNA511598 | ENA
GenomicsmiRNA Expression data from sulfisoxazole-treated breast cancer cell-derived exosome
Sulfisoxazole, a FDA-approved drug, is a promising repositioned drug candidate for the treatement of various cancers. Therefore we analyzed the gene expression by microarray to identified the up-regulated and down-regulated genes after SFX treatment in breast cancer cell-derived exosomes.
ORGANISM(S): Homo sapiens synthetic construct 
2018-12-24 | GSE124320 | GEO
UnknownSulfisoxazole Elicits Robust Antitumour Immune Response Along with Immune Checkpoint Therapy by Inhibiting Exosomal PD-L1.
Not available
S-EPMC8844465 | biostudies-literature
UnknownSulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A.
Not available
S-EPMC6437193 | biostudies-literature
GenomicsEscherichia coli strain:SW4848
Escherichia coli strain:SW4848 Genome sequencing
PRJNA888808 | ENA
UnknownMolecular Docking of Lac_CB10: Highlighting the Great Potential for Bioremediation of Recalcitrant Chemical Compounds by One Predicted Bacteroidetes CopA-Laccase.
Not available
S-EPMC10298561 | biostudies-literature
UnknownMutations in folP associated with elevated sulfonamide MICs for Neisseria meningitidis clinical isolates from five continents.
Not available
S-EPMC547345 | biostudies-literature
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