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MetabolomicsCross-feeding and co-degradation within a bacterial consortium dominated by challenging-to-cultivate Leucobacter sp. HA-1 enhances sulfonamides degradation

Background: The use of sulfonamides (SAs) caused residual pollution in the environment. Bacteria play an important role in the degradation of sulfonamide antibiotics, and microbial consortium offers advantages over single bacterium. However, the complex degradation process and interaction mechani...

2024-11-08 | MTBLS11473 | MetaboLights
GenomicsMechanisms of Risk for Sulfonamide Hypersensitivity
Mechanisms of Risk for Sulfonamide Hypersensitivity
PRJNA322104 | ENA
GenomicsMechanism of the development of sulfonamide resistance
Sulfonamide sensitive bacterial strains were exposed to sub inhibitory sulfonamide concentration to examine the effect of sub inhibitory concentration on the resistance development.
PRJEB40207 | ENA
GenomicsMicrobial community of activated sludge acclimated by sulfonamide
Microbial community of activated sludge acclimated by sulfonamide Raw sequence reads
PRJNA610549 | ENA
GenomicsMicrobial community of activated sludge acclimated by sulfonamide
Microbial community of activated sludge acclimated by sulfonamide Raw sequence reads
PRJNA609592 | ENA
TranscriptomicsRNA Expression Profiling of CD8+ T Cell-Enriched Peripheral Blood Mononuclear Cells from Potentiated Sulfonamide-Treated Patients with a Range of Lymphocyte Cytotoxicity Phenotypes
Hypersensitivity reactions are rare, but potentially severe adverse effects of sulfonamide antibiotics. Increased in vitro toxicity of lymphocytes, primarily CD8+ T cells, to sulfonamide drug metabolites as been proposed as a marker for sulfonamide hypersensitivity, but the mechanisms underlying thi...
ORGANISM(S): Homo sapiens 
2017-06-26 | GSE100443 | GEO
Genomics
sulfonamide resistant bacteria
PRJNA1184938 | ENA
ProteomicsIn vivo fitness of sul gene-dependent sulfonamide-resistant Escherichia coli in the mammalian gut
Sulfonamides are traditional synthetic antimicrobial agents used in clinical and veterinary medical settings. Their long-term excessive overuse has resulted in widespread microbial resistance, limiting their application for medical interventions. Resistance to sulfonamides is primarily conferred by ...
ORGANISM(S): Escherichia Coli Str. K-12 Substr. Mg1655 
2024-07-04 | PXD053633 |
Genomics
sulfonamide antibiotics
PRJNA445360 | ENA
ClinicalChloroquinoxaline Sulfonamide in Treating Patients With Stage IV Colorectal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of chloroquinoxaline sulfonamide in treating patients who have stage IV colorectal cancer.
2004939 | ecrin-mdr-crc
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