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ProteomicsA novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii.
Carbapenem-resistant Acinetobacter baumannii (CRAb) is an urgent public health threat, according to the CDC. This pathogen has few treatment options and causes severe nosocomial infections with >50% fatality rate. Although previous studies have examined the proteome of CRAb, there have been no focus...
ORGANISM(S): Acinetobacter baumannii A424 Bacteria 
2023-07-20 | PXD042336 | Pride
Tims tof pro2 Acinetobacter baumannii Dda lfq 
ProteomicsUnbiased identification of Pleiotrophin-interacting proteins in the brain
Affinity purification-mass spectrometry was performed to identify proteins associated with pleiotrophin in wild-type mouse brain tissue. Ptn and hFc control pulldowns were analyzed to identify specific Ptn-interacting proteins.
ORGANISM(S): Mus musculus (Mouse) 
2026-07-21 | PXD081065 | Pride
Pleiotrophin  mouse brain 
ProteomicsNovel Mechanism and Therapy of Anthracycline-Induced Cardiotoxicity (AIC)
Anthracyclines are potent chemotherapeutic agents known for their efficacy in treating various cancers via inhibition of topoisomerase II alpha (TOP2A). However, their clinical use is limited due to cardiotoxicity, primarily attributed to off-target inhibition of topoisomerase II beta (TOP2B) in car...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-05 | PXD077277 | Pride
Top2b Smyd1 
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