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Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
The healthy heart relies on mitochondrial fatty acid β-oxidation (FAO) for ATP production but can exhibit marked metabolic flexibility in response to diverse physiological and pathological circumstances 1-4. Mutations or deficiencies in FAO enzymes can lead to a spectrum of symptoms, ranging from mu...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-14 | PXD052216 | Pride
Cuproptosis, a recently defined copper-dependent cell death, remains largely unexplored in tumor therapies, particularly in breast cancer. Our study demonstrates that triple-negative breast cancer (TNBC) bears a relative elevated copper levels and exhibit resistance to cuproptosis. Mechanistically, ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058176 | Pride
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