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TranscriptomicsDNA methylation profiling of healthy elderly individuals with different lifestyle habits
Illumina Infinium EPIC HumanMethylation BeadChip data from saliva DNA samples from a healthy elderly cohort with individuals in the age range 70-95 in Southwest Sweden. The cohort was stratified into study groups based on participants´answers to a questionnaire of different lifestyle factors includi...
ORGANISM(S): Homo sapiens 
2022-07-23 | E-MTAB-11445 | biostudies-arrayexpress
UnknownUsing genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk.
Not available
S-EPMC3616836 | biostudies-literature
TranscriptomicsDistinct Sets of Genetic Alterations in Melanoma
We compared genome-wide DNA copy number alterations and mutational status in BRAF and RAS genes of 126 primary melanomas arising in four groups in which UV exposure differ: skin with (n=30), and without chronic sun damage (n=40); palms, soles and subungual (acral) sites (n=36) (which have very littl...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-2631 | biostudies-arrayexpress
TranscriptomicsWhole genome expression data from pre-auricular and post-auricular skin tissues
Photoaging is cumulative damage that is caused by chronic, repeated solar radiation exposure to skin. Its molecular mechanisms are poorly understood at the level of global gene expression.This study set out to uncover genes and functional modules involved in photoaging at the level of transcription,...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-38308 | biostudies-arrayexpress
TranscriptomicsTranscriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human 293T cells
RNA was isolated from and METTL3M-oM-
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-50582 | biostudies-arrayexpress
TranscriptomicsHigh salt primes a specific activation state of macrophages, M(Na)
Purpose: Investigate effects of high salt on human macrophage activation Methods: Human monocytes-derived macrophages were treated by additional 51mM NaCl for 24 hours (NaCl groups) or not (Control groups). mRNA profiles were generated by RNA-Seq, in triplicate, using Ion proton（Life tech). qRT–PCR ...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-68482 | biostudies-arrayexpress
MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
TranscriptomicsComparison of transcriptomes between Marf1+/+ (WT) and Marf1 ENU/ENU (Mutant) fully-grown oocytes (FGO)
Marf1 (MUT) female mice are infertile and the meiosis of the oocytes are arrest at prophase I. We thought to identify the potential causes of the meiotic arrest phenotype in the mutant oocytes by comparing the transcriptomes of the WT and mutant fully-grown oocytes (from 23-d old mice) that are tran...
ORGANISM(S): Mus musculus 
2012-03-30 | E-GEOD-31985 | biostudies-arrayexpress
UnknownCathelicidin-DM is an Antimicrobial Peptide from Duttaphrynus melanostictus and Has Wound-Healing Therapeutic Potential.
Not available
S-EPMC7191562 | biostudies-literature
TranscriptomicsTNF-M-NM-1 treated HUVECs: microRNA negative control VS. miR-181b
Transcriptional profiling of TNF-M-NM-1 treated HUVECs comparing cells transfected microRNA negative control with cells transfected with miR-181b. Two-condition experiment, miR negative control VS. miR-181b transfected HUVECs. Biological replicates: 4 replicates of comparison of miR negative contro...
ORGANISM(S): Homo sapiens 
2012-05-15 | E-GEOD-35030 | biostudies-arrayexpress
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