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TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in mRNA vaccinated individuals post BA.1-breakthrough infection
Memory B cells play a fundamental role in host defenses against viruses. This dataset aimed at understanding the recruitment and remodeling of the memory B cell repertoire in the context of BA.1-breakthrough infection in BNT162b2 mRNA vaccinated individuals. All four donors enrolled in the study had...
ORGANISM(S): Homo sapiens 
2023-08-15 | E-MTAB-12651 | biostudies-arrayexpress
TranscriptomicsThe genetic landscape of mutations in Burkitt lymphoma
Burkitt lymphoma is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is largely unknown. Here, we describe the first completely sequenced genome from a Burkitt lymphoma tumor and germline DNA from the same affected individual. We further sequen...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-48435 | biostudies-arrayexpress
TranscriptomicsValidation of a genomic classifier that predicts metastasis following radical prostatectomy in at risk patient population
Purpose: Patients with locally advanced prostate cancer after radical prostatectomy are candidates for secondary therapy. However, this higher risk population is heterogeneous. Many cases do not metastasize even when conservatively managed. Given the limited specificity of pathological features to p...
ORGANISM(S): Homo sapiens 
2014-11-13 | E-GEOD-62116 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Streptococcus pneumoniae TCS08 mutant (disrupted in rr08) compared to the parent wild type strain TIGR4
Transcriptional changes of an TCS08 mutant (disrupted in rr08) compared to the parent wild-type strain TIGR4 when both strains were cultured to early logarithmic growth phase in THY broth.
ORGANISM(S): Streptococcus pneumoniae 
2008-12-20 | E-FPMI-17 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. pneumonia strain TIGR4 early response to human A549 lung epithelial cells
Transcriptional responses of Streptococcus pneumoniae strain TIGR4 to human lung epithelial cells (A549) were investigated at the early stages of interactions (0.5 h and 1 h).
ORGANISM(S): Streptococcus pneumoniae 
2008-09-30 | E-FPMI-15 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. pneumonia early response to to THP-1 human macrophages
Transcriptional responses of an unencapsulated Streptococcus pneumoniae strain derived from TIGR4 to human macrophages THP-1 were investigated at the early stages of interactions (0.5 h, 1 h and 3h).
ORGANISM(S): Streptococcus pneumoniae 
2008-10-21 | E-FPMI-16 | biostudies-arrayexpress
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