We performed ChIP-seq on a complex developing tissue (the spinal cord) at mouse embryonic day 12.5. Genome-wide binding sites of Mash1 were generated. ChIP-seq of Mash1/Ascl1 in a heterogeneous tissue.
Recent studies have shown a close relationship between the gut microbiota and Crohn's disease (CD). This study aimed to determine whether mesenchymal stem cell (MSC) treatment alters the gut microbiota and fecal metabolite pathways and to establish the relationship between the gut microbiota and fec...
Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...
The mouse model of septic kidney injury was established by cecal ligation, and the kidney tissue was obtained 12 hours later. The kidney tissue between CLP group and control group was analyzed by mass spectrometry.
