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ProteomicsGPI-Anchored Ligand-BioID2-Tagging System Identifies proteins Mediating Zika Virus Entry
Identification of host factors facilitating pathogen entry is critical for preventing infectious diseases. Here, we report a tagging system consisting of a viral receptor-binding protein (RBP) linked to BioID2, which is expressed on the cell surface via a GPI anchor. Using VSV or Zika virus (ZIKV) R...
ORGANISM(S): Homo Sapiens 
2022-10-12 | PXD037307 |
MetabolomicsMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
TranscriptomicsGene expression analysis of breast cancer cell-lines
Recurrent mutations in histone modifying enzymes in multiple cancer types imply key roles in tumorigenesis. However, the functional relevance of these mutations remains unknown. Here we show that the JARID1B histone H3 lysine 4 demethylase is frequently amplified and overexpressed in luminal breast ...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-45732 | biostudies-arrayexpress
GenomicsGenome-wide location analysis in breast cancer cell-lines
Recurrent mutations in histone modifying enzymes in multiple cancer types imply key roles in tumorigenesis. However, the functional relevance of these mutations remains unknown. Here we show that the JARID1B histone H3 lysine 4 demethylase is frequently amplified and overexpressed in luminal breast ...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-46055 | biostudies-arrayexpress
UnknownFBXO5-mediated RNF183 degradation prevents endoplasmic reticulum stress-induced apoptosis and promotes colon cancer progression.
Not available
S-EPMC10784456 | biostudies-literature
ProteomicsProteomics of lung adenocarcinoma, parapneumonic and tuberculous pleural effusion
To investigate the proteomic and metabolomic profiles of benign and malignant pleural effusions (BPE and MPE), samples were collected from patients in the Department of Respiratory Medicine. The diagnostic confirmation for MPE relied on pleural fluid cytology, thoracoscopy, and pleural biopsy. For t...
ORGANISM(S): Homo Sapiens 
2025-12-03 | PXD071511 |
ProteomicsMetabolomics of lung adenocarcinoma, parapneumonic and tuberculous pleural effusion
To investigate the proteomic and metabolomic profiles of benign and malignant pleural effusions (BPE and MPE), samples were collected from patients in the Department of Respiratory Medicine. The diagnostic confirmation for MPE relied on pleural fluid cytology, thoracoscopy, and pleural biopsy. For t...
ORGANISM(S): Homo Sapiens 
2025-12-03 | PXD071514 |
ProteomicsProteome sequencing of uterus at different eggshell strenghten and thickness of hens
In this study, we employed proteomics to investigate the differences between the uteruses of laying hens with high- or low-breaking-strength shells.
ORGANISM(S): Gallus Gallus 
2020-09-14 | PXD021449 |
UnknownSingle-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer.
Not available
S-EPMC10495415 | biostudies-literature
ProteomicsProteomics dataset of COVID-19 and control patients
Proteomics dataset of COVID-19 and control patients
ORGANISM(S): Homo Sapiens 
2021-10-14 | PXD029023 |
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