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UnknownThe Combined Effects of Hourly Multi-Pollutant on the Risk of Ambulance Emergency Calls: A Seven-Year Time Series Study.
Not available
S-EPMC10675017 | biostudies-literature
ProteomicsImproving quantitative glycoproteomics by systematic evaluation of different glycopeptide enrichment, quantification, and mass spectrometry strategies
In this study, we conducted a systematic investigation into a glycoproteomic workflow. Firstly, Label-free and TMT labeling strategies were utilized for intact N-glycopeptide quantification. A total of 2,924 unique intact N-glycopeptides can be quantified after being labeled using TMT approach. Comp...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-05-07 | PXD054874 | Pride
Glycoproteomics Intact glycopeptide Identification Quantification 
UnknownANP32E induces tumorigenesis of triple-negative breast cancer cells by upregulating E2F1.
Not available
S-EPMC5983205 | biostudies-literature
ProteomicsSystem-wide analysis of SUMOylation dynamics in response to replication stress reveals novel SUMO target proteins and acceptor lysines relevant for genome stability
Genotoxic agents can cause replication fork stalling in dividing cells due to DNA lesions, eventually leading to replication fork collapse when the damage is not repaired. Small Ubiquitin-like Modifiers (SUMOs) are known to counteract replication stress, nevertheless, only a small number of relevant...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080851 | MassIVE
ProteomicsRAN, TDP43 and G3BP1 mRNA form a complex
To identify the candidate that directly stabilizes G3BP1 mRNA, the enriched proteins pulled down by G3BP1 probes and anti-RAN antibody were subjected to mass spectrometry (MS) analysis
ORGANISM(S): Homo Sapiens 
2024-10-01 | PXD056577 |
ProteomicsProximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
Cyclic GMP-AMP synthase (cGAS), as the major DNA sensor, initiates DNA-stimulated innate immune responses and is essential for healthy immune system. Although some regulators of cGAS have been reported, it still remains largely unknown about how cGAS is precisely and dynamically regulated and how ma...
ORGANISM(S): Homo Sapiens 
2023-03-02 | PXD040544 |
Proteomicsone step carboxyl group isotopic labeling for quantitative analysis of N-glycopeptide by Mass Spectrometry
Glycosylation is one of the most common and important post-translational modifications. Quantitative analysis of intact N-glycopeptides is critical to understand the role of protein glycosylation in physiological and pathological processes. In this work, we developed a novel approach called methylam...
ORGANISM(S): Homo Sapiens 
2020-08-25 | PXD021104 |
ProteomicsHigh throughput quantitative analysis of site-specific N-glycosylation reveals glyco-signatures for diagnosis of liver disease
Glycosylation influences diverse life processes and changes in pathological processes. The glycoproteomic has been recognized as a hot area to screen markers as altered glycosylation is a universal feature of cancer cells. However, the high throughput screening of glycosylation markers from a large ...
ORGANISM(S): Homo Sapiens 
2021-07-16 | PXD027379 |
ProteomicsHigh-Throughput Intact Glycopeptide Quantification Strategy with Targeted-MS (HTiGQs-Target) Reveals Site-Specific IgG N-Glycopeptides as Biomarkers for Hepatic Disorder Diagnosis and Staging
We developed a high-throughput targeted quantification strategy for intact glycopeptides (HTiGQs-Target) to diagnose and differentiate the malignancy of liver diseases. The method involves two-step labeling. This step derivatization makes the same parent ions in different samples produce sufficient ...
ORGANISM(S): Homo Sapiens 
2023-05-30 | PXD042528 |
ProteomicsMTH1's role in platelet function
MTH1 knockout mice were utilized to evaluate its role in platelet mitochondrial function and thrombosis
ORGANISM(S): Mus Musculus 
2023-04-14 | PXD041528 |
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